High fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus

A possible relationship between fibrosis along the route of cerebrospinal fluid (CSF) flow and the subsequent development of hydrocephalus has been indicated in previous studies. These changes in the fibrosis index may reflect the severity of hydrocephalus and could potentially become a diagnostic t...

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Autores principales:	Hao Xu, Junwen Wang, Jiaqing Li, Ran Li, Zhuo Zhang, Yimin Huang, Wei Jiao, Wei Sun, Ting Lei
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2016
Materias:	fibrosis hyaluronic acid hydrocephalus laminin procollagen tgf-β1 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/e39b64096ea44500b916f391e5f614b7
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spelling	oai:doaj.org-article:e39b64096ea44500b916f391e5f614b72021-12-05T14:11:04ZHigh fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus2081-693610.1515/tnsci-2016-0015https://doaj.org/article/e39b64096ea44500b916f391e5f614b72016-01-01T00:00:00Zhttps://doi.org/10.1515/tnsci-2016-0015https://doaj.org/toc/2081-6936A possible relationship between fibrosis along the route of cerebrospinal fluid (CSF) flow and the subsequent development of hydrocephalus has been indicated in previous studies. These changes in the fibrosis index may reflect the severity of hydrocephalus and could potentially become a diagnostic tool. The object of this study was to analyze the levels of procollagen type I C-terminal propeptide (PICP), procollagen type III N-terminal propeptide (PIIINP), hyaluronic acid (HA), and laminin (LN) in the CSF of patients with post-traumatic hydrocephalus and determine the significance of their presence.Hao XuJunwen WangJiaqing LiRan LiZhuo ZhangYimin HuangWei JiaoWei SunTing LeiDe Gruyterarticlefibrosishyaluronic acidhydrocephaluslamininprocollagentgf-β1Neurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENTranslational Neuroscience, Vol 7, Iss 1, Pp 92-97 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	fibrosis hyaluronic acid hydrocephalus laminin procollagen tgf-β1 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	fibrosis hyaluronic acid hydrocephalus laminin procollagen tgf-β1 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Hao Xu Junwen Wang Jiaqing Li Ran Li Zhuo Zhang Yimin Huang Wei Jiao Wei Sun Ting Lei High fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus
description	A possible relationship between fibrosis along the route of cerebrospinal fluid (CSF) flow and the subsequent development of hydrocephalus has been indicated in previous studies. These changes in the fibrosis index may reflect the severity of hydrocephalus and could potentially become a diagnostic tool. The object of this study was to analyze the levels of procollagen type I C-terminal propeptide (PICP), procollagen type III N-terminal propeptide (PIIINP), hyaluronic acid (HA), and laminin (LN) in the CSF of patients with post-traumatic hydrocephalus and determine the significance of their presence.
format	article
author	Hao Xu Junwen Wang Jiaqing Li Ran Li Zhuo Zhang Yimin Huang Wei Jiao Wei Sun Ting Lei
author_facet	Hao Xu Junwen Wang Jiaqing Li Ran Li Zhuo Zhang Yimin Huang Wei Jiao Wei Sun Ting Lei
author_sort	Hao Xu
title	High fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus
title_short	High fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus
title_full	High fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus
title_fullStr	High fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus
title_full_unstemmed	High fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus
title_sort	high fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus
publisher	De Gruyter
publishDate	2016
url	https://doaj.org/article/e39b64096ea44500b916f391e5f614b7
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High fibrosis indices in cerebrospinal fluid of patients with shunt-dependent post-traumatic chronic hydrocephalus

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