Loss of Upc2p-Inducible <italic toggle="yes">ERG3</italic> Transcription Is Sufficient To Confer Niche-Specific Azole Resistance without Compromising <named-content content-type="genus-species">Candida albicans</named-content> Pathogenicity
ABSTRACT Inactivation of sterol Δ5,6-desaturase (Erg3p) in the prevalent fungal pathogen Candida albicans is one of several mechanisms that can confer resistance to the azole antifungal drugs. However, loss of Erg3p activity is also associated with deficiencies in stress tolerance, invasive hyphal g...
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| Autores principales: | , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2018
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/e3a04b7a36c249fbbe3ef214803936ec |
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