Pyrrolizine/Indolizine-NSAID Hybrids: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies
In the current study, eight new hybrids of the NSAIDs, ibuprofen and ketoprofen with five pyrrolizine/indolizine derivatives were designed and synthesized. The chemical structures of these hybrids were confirmed by spectral and elemental analyses. The antiproliferative activities of these hybrids (5...
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Auteurs principaux: | Mohammed A. S. Abourehab, Alaa M. Alqahtani, Faisal A. Almalki, Dana M. Zaher, Ashraf N. Abdalla, Ahmed M. Gouda, Eman A. M. Beshr |
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Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
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Sujets: | |
Accès en ligne: | https://doaj.org/article/e3a501d1abb7432fba45b181cbc1b84d |
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