E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family

E2F transcription factors are regulators of cell division and cell fate decisions. Here the authors show that E2F4 is important for proliferation and survival of mouse ESCs, independent of the RB family, and that E2F4 interacts with chromatin regulators associated with gene activation.

Guardado en:

Detalles Bibliográficos
Autores principales:	Jenny Hsu, Julia Arand, Andrea Chaikovsky, Nancie A. Mooney, Janos Demeter, Caileen M. Brison, Romane Oliverio, Hannes Vogel, Seth M. Rubin, Peter K. Jackson, Julien Sage
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3a619fadabb47e3805fe00dc38b37d4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e3a619fadabb47e3805fe00dc38b37d4
record_format	dspace
spelling	oai:doaj.org-article:e3a619fadabb47e3805fe00dc38b37d42021-12-02T15:36:18ZE2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family10.1038/s41467-019-10901-x2041-1723https://doaj.org/article/e3a619fadabb47e3805fe00dc38b37d42019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10901-xhttps://doaj.org/toc/2041-1723E2F transcription factors are regulators of cell division and cell fate decisions. Here the authors show that E2F4 is important for proliferation and survival of mouse ESCs, independent of the RB family, and that E2F4 interacts with chromatin regulators associated with gene activation.Jenny HsuJulia ArandAndrea ChaikovskyNancie A. MooneyJanos DemeterCaileen M. BrisonRomane OliverioHannes VogelSeth M. RubinPeter K. JacksonJulien SageNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jenny Hsu Julia Arand Andrea Chaikovsky Nancie A. Mooney Janos Demeter Caileen M. Brison Romane Oliverio Hannes Vogel Seth M. Rubin Peter K. Jackson Julien Sage E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family
description	E2F transcription factors are regulators of cell division and cell fate decisions. Here the authors show that E2F4 is important for proliferation and survival of mouse ESCs, independent of the RB family, and that E2F4 interacts with chromatin regulators associated with gene activation.
format	article
author	Jenny Hsu Julia Arand Andrea Chaikovsky Nancie A. Mooney Janos Demeter Caileen M. Brison Romane Oliverio Hannes Vogel Seth M. Rubin Peter K. Jackson Julien Sage
author_facet	Jenny Hsu Julia Arand Andrea Chaikovsky Nancie A. Mooney Janos Demeter Caileen M. Brison Romane Oliverio Hannes Vogel Seth M. Rubin Peter K. Jackson Julien Sage
author_sort	Jenny Hsu
title	E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family
title_short	E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family
title_full	E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family
title_fullStr	E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family
title_full_unstemmed	E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family
title_sort	e2f4 regulates transcriptional activation in mouse embryonic stem cells independently of the rb family
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/e3a619fadabb47e3805fe00dc38b37d4
work_keys_str_mv	AT jennyhsu e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT juliaarand e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT andreachaikovsky e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT nancieamooney e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT janosdemeter e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT caileenmbrison e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT romaneoliverio e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT hannesvogel e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT sethmrubin e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT peterkjackson e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily AT juliensage e2f4regulatestranscriptionalactivationinmouseembryonicstemcellsindependentlyoftherbfamily
_version_	1718386386838487040

E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family

Ejemplares similares