Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer Networks

Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer Networks

Abstract Emerging evidence indicates the existence of a new class of cancer genes that act as “signal linkers” coordinating oncogenic signals between mutated and differentially expressed genes. While frequently mutated oncogenes and differentially expressed genes, which we term Class I cancer genes,...

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Autores principales: Mehrab Ghanat Bari, Choong Yong Ung, Cheng Zhang, Shizhen Zhu, Hu Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e3b591ea664e4688aa46a019ac64179c
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