Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase
Abstract Intestinal epithelial barrier properties are maintained by a junctional complex consisting of tight junctions (TJ), adherens junctions (AJ) and desmosomes. Desmoglein 2 (Dsg2), an adhesion molecule of desmosomes and the only Dsg isoform expressed in enterocytes, is required for epithelial b...
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Main Authors: | Hanna Ungewiß, Franziska Vielmuth, Shintaro T. Suzuki, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Daniela Kugelmann, Nicolas Schlegel, Jens Waschke |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/e3bf6cdb8c36482bbd4222776e21ef8f |
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