Leptin levels in gingival crevicular fluid during orthodontic tooth movement

Aim: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement. Materials and Methods: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment,...

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Autores principales: Joseph Alaguselvaraj, Kandanraj Selvaraj, Porselvi Bhaskaran, Sainath Muthiah Chidambaram, Thanigainathan Rajasekaran, Muralimani Mani
Formato: article
Lenguaje:EN
Publicado: Wolters Kluwer Medknow Publications 2021
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Acceso en línea:https://doaj.org/article/e3c4f1a6404c422498c6014e97d36fc2
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Sumario:Aim: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement. Materials and Methods: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment, (B) 6 h after applying retractive orthodontic force from right side canine, (C) without retractive force from left side canine, and after 21 days from right canine (D), and left canine (E). Results: GCF Leptin concentration in pretreatment, 6 h control and 21st day control were all similar. GCF leptin concentration at 6 h test tooth site was increased which was statistically significant. GCF leptin concentration in 21st day test tooth was decreased only a little than the control tooth which shows statistically no difference. Conclusion: Leptin is one of the mediators of orthodontic tooth movement.