Neutrophils dominate the immune cell composition in non-small cell lung cancer

Tumour immune evasion can involve multiple strategies. Here, the authors characterize the immune populations from clinical specimens of lung cancer in conjunction with TCR-β sequencing and show abundant neutrophils affecting cytotoxic T-cell content and the frequent presence of tumour-specific T-cel...

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Autores principales:	Julia Kargl, Stephanie E. Busch, Grace H. Y. Yang, Kyoung-Hee Kim, Mark L. Hanke, Heather E. Metz, Jesse J. Hubbard, Sylvia M. Lee, David K. Madtes, Martin W. McIntosh, A. McGarry Houghton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3ccc629fbf04585997cc516e4b37d35
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spelling	oai:doaj.org-article:e3ccc629fbf04585997cc516e4b37d352021-12-02T15:37:06ZNeutrophils dominate the immune cell composition in non-small cell lung cancer10.1038/ncomms143812041-1723https://doaj.org/article/e3ccc629fbf04585997cc516e4b37d352017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14381https://doaj.org/toc/2041-1723Tumour immune evasion can involve multiple strategies. Here, the authors characterize the immune populations from clinical specimens of lung cancer in conjunction with TCR-β sequencing and show abundant neutrophils affecting cytotoxic T-cell content and the frequent presence of tumour-specific T-cell clones.Julia KarglStephanie E. BuschGrace H. Y. YangKyoung-Hee KimMark L. HankeHeather E. MetzJesse J. HubbardSylvia M. LeeDavid K. MadtesMartin W. McIntoshA. McGarry HoughtonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julia Kargl Stephanie E. Busch Grace H. Y. Yang Kyoung-Hee Kim Mark L. Hanke Heather E. Metz Jesse J. Hubbard Sylvia M. Lee David K. Madtes Martin W. McIntosh A. McGarry Houghton Neutrophils dominate the immune cell composition in non-small cell lung cancer
description	Tumour immune evasion can involve multiple strategies. Here, the authors characterize the immune populations from clinical specimens of lung cancer in conjunction with TCR-β sequencing and show abundant neutrophils affecting cytotoxic T-cell content and the frequent presence of tumour-specific T-cell clones.
format	article
author	Julia Kargl Stephanie E. Busch Grace H. Y. Yang Kyoung-Hee Kim Mark L. Hanke Heather E. Metz Jesse J. Hubbard Sylvia M. Lee David K. Madtes Martin W. McIntosh A. McGarry Houghton
author_facet	Julia Kargl Stephanie E. Busch Grace H. Y. Yang Kyoung-Hee Kim Mark L. Hanke Heather E. Metz Jesse J. Hubbard Sylvia M. Lee David K. Madtes Martin W. McIntosh A. McGarry Houghton
author_sort	Julia Kargl
title	Neutrophils dominate the immune cell composition in non-small cell lung cancer
title_short	Neutrophils dominate the immune cell composition in non-small cell lung cancer
title_full	Neutrophils dominate the immune cell composition in non-small cell lung cancer
title_fullStr	Neutrophils dominate the immune cell composition in non-small cell lung cancer
title_full_unstemmed	Neutrophils dominate the immune cell composition in non-small cell lung cancer
title_sort	neutrophils dominate the immune cell composition in non-small cell lung cancer
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e3ccc629fbf04585997cc516e4b37d35
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Neutrophils dominate the immune cell composition in non-small cell lung cancer

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