The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells

The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells

Abstract Most of over a thousand mitochondrial proteins are encoded by nuclear genes and must be imported from the cytosol. Little is known about the cytosolic events regulating mitochondrial protein import, partly due to the lack of appropriate tools for its assessment in living cells. We engineere...

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Autores principales: M. Jacoupy, E. Hamon-Keromen, A. Ordureau, Z. Erpapazoglou, F. Coge, J.-C. Corvol, O. Nosjean, C. Mannoury la Cour, M. J. Millan, J. A. Boutin, J. W. Harper, A. Brice, D. Guedin, C. A. Gautier, O. Corti
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e3de579c73004127a500e989a78a21a9
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