Affinity and competition for TBP are molecular determinants of gene expression noise

TATA boxes in gene promoters are associated with high level of cell-to-cell variation in gene expression. Through integration of multiple data sets, the authors now provide insights into how the interactions of TBP with DNA and other proteins can lead to noisy expression.

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Autores principales:	Charles N. J. Ravarani, Guilhem Chalancon, Michal Breker, Natalia Sanchez de Groot, M. Madan Babu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3e7cf8d13c14af0856ae4db82ef2db9
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spelling	oai:doaj.org-article:e3e7cf8d13c14af0856ae4db82ef2db92021-12-02T14:39:51ZAffinity and competition for TBP are molecular determinants of gene expression noise10.1038/ncomms104172041-1723https://doaj.org/article/e3e7cf8d13c14af0856ae4db82ef2db92016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10417https://doaj.org/toc/2041-1723TATA boxes in gene promoters are associated with high level of cell-to-cell variation in gene expression. Through integration of multiple data sets, the authors now provide insights into how the interactions of TBP with DNA and other proteins can lead to noisy expression.Charles N. J. RavaraniGuilhem ChalanconMichal BrekerNatalia Sanchez de GrootM. Madan BabuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Charles N. J. Ravarani Guilhem Chalancon Michal Breker Natalia Sanchez de Groot M. Madan Babu Affinity and competition for TBP are molecular determinants of gene expression noise
description	TATA boxes in gene promoters are associated with high level of cell-to-cell variation in gene expression. Through integration of multiple data sets, the authors now provide insights into how the interactions of TBP with DNA and other proteins can lead to noisy expression.
format	article
author	Charles N. J. Ravarani Guilhem Chalancon Michal Breker Natalia Sanchez de Groot M. Madan Babu
author_facet	Charles N. J. Ravarani Guilhem Chalancon Michal Breker Natalia Sanchez de Groot M. Madan Babu
author_sort	Charles N. J. Ravarani
title	Affinity and competition for TBP are molecular determinants of gene expression noise
title_short	Affinity and competition for TBP are molecular determinants of gene expression noise
title_full	Affinity and competition for TBP are molecular determinants of gene expression noise
title_fullStr	Affinity and competition for TBP are molecular determinants of gene expression noise
title_full_unstemmed	Affinity and competition for TBP are molecular determinants of gene expression noise
title_sort	affinity and competition for tbp are molecular determinants of gene expression noise
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/e3e7cf8d13c14af0856ae4db82ef2db9
work_keys_str_mv	AT charlesnjravarani affinityandcompetitionfortbparemoleculardeterminantsofgeneexpressionnoise AT guilhemchalancon affinityandcompetitionfortbparemoleculardeterminantsofgeneexpressionnoise AT michalbreker affinityandcompetitionfortbparemoleculardeterminantsofgeneexpressionnoise AT nataliasanchezdegroot affinityandcompetitionfortbparemoleculardeterminantsofgeneexpressionnoise AT mmadanbabu affinityandcompetitionfortbparemoleculardeterminantsofgeneexpressionnoise
_version_	1718390508246532096

Affinity and competition for TBP are molecular determinants of gene expression noise

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