Affinity and competition for TBP are molecular determinants of gene expression noise

TATA boxes in gene promoters are associated with high level of cell-to-cell variation in gene expression. Through integration of multiple data sets, the authors now provide insights into how the interactions of TBP with DNA and other proteins can lead to noisy expression.

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Auteurs principaux: Charles N. J. Ravarani, Guilhem Chalancon, Michal Breker, Natalia Sanchez de Groot, M. Madan Babu
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/e3e7cf8d13c14af0856ae4db82ef2db9
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