Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

MIF is a cytokine best known for its modulatory effect on expression of proinflammatory cytokines. Here the authors show that MIF facilitates the NLRP3–vimentin interaction, resulting in Nlrp3 inflammasome activation.

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Autores principales:	Tali Lang, Jacinta P. W. Lee, Kirstin Elgass, Anita A. Pinar, Michelle D. Tate, Elizabeth H. Aitken, Huapeng Fan, Sarah J. Creed, Nadia S. Deen, Daouda A. K. Traore, Ivo Mueller, Danielle Stanisic, Francesca S. Baiwog, Colin Skene, Matthew C. J. Wilce, Ashley Mansell, Eric F. Morand, James Harris
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e3f4f9c8a1b94be9979682bf263d2d83
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:e3f4f9c8a1b94be9979682bf263d2d832021-12-02T17:31:12ZMacrophage migration inhibitory factor is required for NLRP3 inflammasome activation10.1038/s41467-018-04581-22041-1723https://doaj.org/article/e3f4f9c8a1b94be9979682bf263d2d832018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04581-2https://doaj.org/toc/2041-1723MIF is a cytokine best known for its modulatory effect on expression of proinflammatory cytokines. Here the authors show that MIF facilitates the NLRP3–vimentin interaction, resulting in Nlrp3 inflammasome activation.Tali LangJacinta P. W. LeeKirstin ElgassAnita A. PinarMichelle D. TateElizabeth H. AitkenHuapeng FanSarah J. CreedNadia S. DeenDaouda A. K. TraoreIvo MuellerDanielle StanisicFrancesca S. BaiwogColin SkeneMatthew C. J. WilceAshley MansellEric F. MorandJames HarrisNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tali Lang Jacinta P. W. Lee Kirstin Elgass Anita A. Pinar Michelle D. Tate Elizabeth H. Aitken Huapeng Fan Sarah J. Creed Nadia S. Deen Daouda A. K. Traore Ivo Mueller Danielle Stanisic Francesca S. Baiwog Colin Skene Matthew C. J. Wilce Ashley Mansell Eric F. Morand James Harris Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
description	MIF is a cytokine best known for its modulatory effect on expression of proinflammatory cytokines. Here the authors show that MIF facilitates the NLRP3–vimentin interaction, resulting in Nlrp3 inflammasome activation.
format	article
author	Tali Lang Jacinta P. W. Lee Kirstin Elgass Anita A. Pinar Michelle D. Tate Elizabeth H. Aitken Huapeng Fan Sarah J. Creed Nadia S. Deen Daouda A. K. Traore Ivo Mueller Danielle Stanisic Francesca S. Baiwog Colin Skene Matthew C. J. Wilce Ashley Mansell Eric F. Morand James Harris
author_facet	Tali Lang Jacinta P. W. Lee Kirstin Elgass Anita A. Pinar Michelle D. Tate Elizabeth H. Aitken Huapeng Fan Sarah J. Creed Nadia S. Deen Daouda A. K. Traore Ivo Mueller Danielle Stanisic Francesca S. Baiwog Colin Skene Matthew C. J. Wilce Ashley Mansell Eric F. Morand James Harris
author_sort	Tali Lang
title	Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
title_short	Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
title_full	Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
title_fullStr	Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
title_full_unstemmed	Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
title_sort	macrophage migration inhibitory factor is required for nlrp3 inflammasome activation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e3f4f9c8a1b94be9979682bf263d2d83
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Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

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