Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states

The chromatin functional state can be derived from the binding patterns of chromatin factors. Here, Zhou and Troyanskaya report a data-driven probabilistic modelling of dependencies between chromatin factors that can divide enhancer-like chromatin states into three functionally distinct groups.

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Detalles Bibliográficos
Autores principales: Jian Zhou, Olga G. Troyanskaya
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/e3fb02d41eed42099ca98ac42107e3ab
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Sumario:The chromatin functional state can be derived from the binding patterns of chromatin factors. Here, Zhou and Troyanskaya report a data-driven probabilistic modelling of dependencies between chromatin factors that can divide enhancer-like chromatin states into three functionally distinct groups.