Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states

The chromatin functional state can be derived from the binding patterns of chromatin factors. Here, Zhou and Troyanskaya report a data-driven probabilistic modelling of dependencies between chromatin factors that can divide enhancer-like chromatin states into three functionally distinct groups.

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Autores principales: Jian Zhou, Olga G. Troyanskaya
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/e3fb02d41eed42099ca98ac42107e3ab
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spelling oai:doaj.org-article:e3fb02d41eed42099ca98ac42107e3ab2021-12-02T16:49:26ZProbabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states10.1038/ncomms105282041-1723https://doaj.org/article/e3fb02d41eed42099ca98ac42107e3ab2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10528https://doaj.org/toc/2041-1723The chromatin functional state can be derived from the binding patterns of chromatin factors. Here, Zhou and Troyanskaya report a data-driven probabilistic modelling of dependencies between chromatin factors that can divide enhancer-like chromatin states into three functionally distinct groups.Jian ZhouOlga G. TroyanskayaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jian Zhou
Olga G. Troyanskaya
Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states
description The chromatin functional state can be derived from the binding patterns of chromatin factors. Here, Zhou and Troyanskaya report a data-driven probabilistic modelling of dependencies between chromatin factors that can divide enhancer-like chromatin states into three functionally distinct groups.
format article
author Jian Zhou
Olga G. Troyanskaya
author_facet Jian Zhou
Olga G. Troyanskaya
author_sort Jian Zhou
title Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states
title_short Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states
title_full Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states
title_fullStr Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states
title_full_unstemmed Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states
title_sort probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/e3fb02d41eed42099ca98ac42107e3ab
work_keys_str_mv AT jianzhou probabilisticmodellingofchromatincodelandscaperevealsfunctionaldiversityofenhancerlikechromatinstates
AT olgagtroyanskaya probabilisticmodellingofchromatincodelandscaperevealsfunctionaldiversityofenhancerlikechromatinstates
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