Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states
The chromatin functional state can be derived from the binding patterns of chromatin factors. Here, Zhou and Troyanskaya report a data-driven probabilistic modelling of dependencies between chromatin factors that can divide enhancer-like chromatin states into three functionally distinct groups.
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Nature Portfolio
2016
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oai:doaj.org-article:e3fb02d41eed42099ca98ac42107e3ab2021-12-02T16:49:26ZProbabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states10.1038/ncomms105282041-1723https://doaj.org/article/e3fb02d41eed42099ca98ac42107e3ab2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10528https://doaj.org/toc/2041-1723The chromatin functional state can be derived from the binding patterns of chromatin factors. Here, Zhou and Troyanskaya report a data-driven probabilistic modelling of dependencies between chromatin factors that can divide enhancer-like chromatin states into three functionally distinct groups.Jian ZhouOlga G. TroyanskayaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
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Science Q Jian Zhou Olga G. Troyanskaya Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states |
description |
The chromatin functional state can be derived from the binding patterns of chromatin factors. Here, Zhou and Troyanskaya report a data-driven probabilistic modelling of dependencies between chromatin factors that can divide enhancer-like chromatin states into three functionally distinct groups. |
format |
article |
author |
Jian Zhou Olga G. Troyanskaya |
author_facet |
Jian Zhou Olga G. Troyanskaya |
author_sort |
Jian Zhou |
title |
Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states |
title_short |
Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states |
title_full |
Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states |
title_fullStr |
Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states |
title_full_unstemmed |
Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states |
title_sort |
probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/e3fb02d41eed42099ca98ac42107e3ab |
work_keys_str_mv |
AT jianzhou probabilisticmodellingofchromatincodelandscaperevealsfunctionaldiversityofenhancerlikechromatinstates AT olgagtroyanskaya probabilisticmodellingofchromatincodelandscaperevealsfunctionaldiversityofenhancerlikechromatinstates |
_version_ |
1718383368507228160 |