Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
Anti-CRISPR proteins offer the means of regulating CRISPR-Cas9 activity. Here the authors present the structure and biochemical characterisation of AcrIIC2 Nme alone and in complex with Cas9.
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Main Authors: | Annoj Thavalingam, Zhi Cheng, Bianca Garcia, Xue Huang, Megha Shah, Wei Sun, Min Wang, Lucas Harrington, Sungwon Hwang, Yurima Hidalgo-Reyes, Erik J. Sontheimer, Jennifer Doudna, Alan R. Davidson, Trevor F. Moraes, Yanli Wang, Karen L. Maxwell |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Online Access: | https://doaj.org/article/e4066aeabab14fe3b824f6c38d4f8d8d |
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