Predictive value of N-terminal pro-B-type natriuretic peptide (NT-pro BNP) combined with D-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention

Acute coronary syndrome (ACS) is a critical illness in cardiovascular disease. The purpose of this study was to investigate the value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and D-dimer in predicting the occurrence of no reflow in emergency percutaneous coronary intervention (PCI) i...

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Autores principales:	Yujing Diao, Meifeng Yin, Baoguo Zhang, Bin Sun
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2021
Materias:	acute coronary syndrome percutaneous coronary intervention nt-probnp d-dimer no-reflow phenomenon Biotechnology TP248.13-248.65
Acceso en línea:	https://doaj.org/article/e408c43970dd4557962b335770596105
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spelling	oai:doaj.org-article:e408c43970dd4557962b3357705961052021-11-04T15:51:53ZPredictive value of N-terminal pro-B-type natriuretic peptide (NT-pro BNP) combined with D-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention2165-59792165-598710.1080/21655979.2021.1988361https://doaj.org/article/e408c43970dd4557962b3357705961052021-01-01T00:00:00Zhttp://dx.doi.org/10.1080/21655979.2021.1988361https://doaj.org/toc/2165-5979https://doaj.org/toc/2165-5987Acute coronary syndrome (ACS) is a critical illness in cardiovascular disease. The purpose of this study was to investigate the value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and D-dimer in predicting the occurrence of no reflow in emergency percutaneous coronary intervention (PCI) in patients with ACS. One hundred and sixty-eight ACS patients were recruited, including 88 patients with normal reflow and 80 patients with no reflow after emergency PCI. The levels of serum NT-proBNP and D-dimer in the patients were detected before PCI, immediately after PCI, 2 hours, and 6 months after PCI. The ROC curve was used to evaluate the predictive value of NT-proBNP and D-dimer in no-reflow phenomenon. Logistic regression model was used to analyze the independent influencing factors of no reflow phenomenon. Logistic regression analysis confirmed that NT-proBNP and D-dimer were independent predictors of the occurrence of no reflow in the total population. The ROC curve showed that the AUC value was 0.909 when NT-proBNP combined with D-dimer. The detection of NT-proBNP combined with D-dimer was helpful to predict the occurrence of no-reflow phenomenon after emergency PCI in ACS patients.Yujing DiaoMeifeng YinBaoguo ZhangBin SunTaylor & Francis Grouparticleacute coronary syndromepercutaneous coronary interventionnt-probnpd-dimerno-reflow phenomenonBiotechnologyTP248.13-248.65ENBioengineered, Vol 12, Iss 1, Pp 8614-8621 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	acute coronary syndrome percutaneous coronary intervention nt-probnp d-dimer no-reflow phenomenon Biotechnology TP248.13-248.65
spellingShingle	acute coronary syndrome percutaneous coronary intervention nt-probnp d-dimer no-reflow phenomenon Biotechnology TP248.13-248.65 Yujing Diao Meifeng Yin Baoguo Zhang Bin Sun Predictive value of N-terminal pro-B-type natriuretic peptide (NT-pro BNP) combined with D-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention
description	Acute coronary syndrome (ACS) is a critical illness in cardiovascular disease. The purpose of this study was to investigate the value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and D-dimer in predicting the occurrence of no reflow in emergency percutaneous coronary intervention (PCI) in patients with ACS. One hundred and sixty-eight ACS patients were recruited, including 88 patients with normal reflow and 80 patients with no reflow after emergency PCI. The levels of serum NT-proBNP and D-dimer in the patients were detected before PCI, immediately after PCI, 2 hours, and 6 months after PCI. The ROC curve was used to evaluate the predictive value of NT-proBNP and D-dimer in no-reflow phenomenon. Logistic regression model was used to analyze the independent influencing factors of no reflow phenomenon. Logistic regression analysis confirmed that NT-proBNP and D-dimer were independent predictors of the occurrence of no reflow in the total population. The ROC curve showed that the AUC value was 0.909 when NT-proBNP combined with D-dimer. The detection of NT-proBNP combined with D-dimer was helpful to predict the occurrence of no-reflow phenomenon after emergency PCI in ACS patients.
format	article
author	Yujing Diao Meifeng Yin Baoguo Zhang Bin Sun
author_facet	Yujing Diao Meifeng Yin Baoguo Zhang Bin Sun
author_sort	Yujing Diao
title	Predictive value of N-terminal pro-B-type natriuretic peptide (NT-pro BNP) combined with D-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention
title_short	Predictive value of N-terminal pro-B-type natriuretic peptide (NT-pro BNP) combined with D-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention
title_full	Predictive value of N-terminal pro-B-type natriuretic peptide (NT-pro BNP) combined with D-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention
title_fullStr	Predictive value of N-terminal pro-B-type natriuretic peptide (NT-pro BNP) combined with D-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention
title_full_unstemmed	Predictive value of N-terminal pro-B-type natriuretic peptide (NT-pro BNP) combined with D-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention
title_sort	predictive value of n-terminal pro-b-type natriuretic peptide (nt-pro bnp) combined with d-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention
publisher	Taylor & Francis Group
publishDate	2021
url	https://doaj.org/article/e408c43970dd4557962b335770596105
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Predictive value of N-terminal pro-B-type natriuretic peptide (NT-pro BNP) combined with D-dimer for no-reflow phenomenon in patients with acute coronary syndrome after emergency of percutaneous coronary intervention

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