Hypoxia stimulates the migration and invasion of osteosarcoma via up-regulating the NUSAP1 expression

Hypoxia stimulates the migration and invasion of osteosarcoma via up-regulating the NUSAP1 expression

Osteosarcoma is a highly aggressive malignant tumor, which most commonly occurs in children and adolescents. This study aims to reveal that hypoxia promotes the invasion of osteosarcoma cells by up-regulating the expression of NUSAP1. The expression of HIF-1α and NUSAP1 was significantly up-regulate...

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Autores principales: Zhang Ling, Song Jingtao, Xin Xu, Sun Donghong, Huang Huiting, Chen Yang, Zhang Tao, Zhang Yiming
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
Materias:
osteosarcoma
hypoxia
hif-1α
nusap1
migration
invasion
Medicine
R
Acceso en línea:https://doaj.org/article/e42794eaa9c94b47bb3a69870d22f8d6
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