Kinetics and specificity of paternal mitochondrial elimination in Caenorhabditis elegans

Autophagy mediates the degradation of paternal mitochondria after fertilization in C. elegansto ensure that mitochondria are inherited maternally. Here the authors show that mitochondrial dynamics is critical for the selectivity and kinetics of paternal mitochondrial elimination.

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Autores principales: Yang Wang, Yi Zhang, Lianwan Chen, Qian Liang, Xiao-Ming Yin, Long Miao, Byung-Ho Kang, Ding Xue
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/e42a05b4d0904c7684c0aa6ed1fef689
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Sumario:Autophagy mediates the degradation of paternal mitochondria after fertilization in C. elegansto ensure that mitochondria are inherited maternally. Here the authors show that mitochondrial dynamics is critical for the selectivity and kinetics of paternal mitochondrial elimination.