Low openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression.

<h4>Background</h4>Recently, we reported that low reward dependence, and to a lesser extent, low cooperativeness in the Temperature and Character Inventory (TCI) may be risk factors for treatment-resistant depression. Here, we analyzed additional psychological traits in these patients.&l...

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Autores principales: Michio Takahashi, Yukihiko Shirayama, Katsumasa Muneoka, Masatoshi Suzuki, Koichi Sato, Kenji Hashimoto
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Publicado: Public Library of Science (PLoS) 2013
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spelling oai:doaj.org-article:e4332b6fc6544d82a5c367574b9e660c2021-11-18T08:57:17ZLow openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression.1932-620310.1371/journal.pone.0071964https://doaj.org/article/e4332b6fc6544d82a5c367574b9e660c2013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24019864/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Recently, we reported that low reward dependence, and to a lesser extent, low cooperativeness in the Temperature and Character Inventory (TCI) may be risk factors for treatment-resistant depression. Here, we analyzed additional psychological traits in these patients.<h4>Methods</h4>We administered Costa and McCrae's five-factor model personality inventory, NEO Personality Inventory-Revised (NEO-PI-R), to antidepressant-treatment resistant depressed patients (n=35), remitted depressed patients (n=27), and healthy controls (n=66). We also evaluated the relationships between scores on NEO and TCI, using the same cohort of patients with treatment-resistant depression, as our previous study.<h4>Results</h4>Patients with treatment-resistant depression showed high scores for neuroticism, low scores for extraversion, openness and conscientiousness, without changes in agreeableness, on the NEO. However, patients in remitted depression showed no significant scores on NEO. Patients with treatment-resistant depression and low openness on NEO showed positive relationships with reward dependence and cooperativeness on the TCI.<h4>Conclusions</h4>Many studies have reported that depressed patients show high neuroticism, low extraversion and low conscientiousness on the NEO. Our study highlights low openness on the NEO, as a risk mediator in treatment-resistant depression. This newly identified trait should be included as a risk factor in treatment-resistant depression.Michio TakahashiYukihiko ShirayamaKatsumasa MuneokaMasatoshi SuzukiKoichi SatoKenji HashimotoPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 9, p e71964 (2013)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Michio Takahashi
Yukihiko Shirayama
Katsumasa Muneoka
Masatoshi Suzuki
Koichi Sato
Kenji Hashimoto
Low openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression.
description <h4>Background</h4>Recently, we reported that low reward dependence, and to a lesser extent, low cooperativeness in the Temperature and Character Inventory (TCI) may be risk factors for treatment-resistant depression. Here, we analyzed additional psychological traits in these patients.<h4>Methods</h4>We administered Costa and McCrae's five-factor model personality inventory, NEO Personality Inventory-Revised (NEO-PI-R), to antidepressant-treatment resistant depressed patients (n=35), remitted depressed patients (n=27), and healthy controls (n=66). We also evaluated the relationships between scores on NEO and TCI, using the same cohort of patients with treatment-resistant depression, as our previous study.<h4>Results</h4>Patients with treatment-resistant depression showed high scores for neuroticism, low scores for extraversion, openness and conscientiousness, without changes in agreeableness, on the NEO. However, patients in remitted depression showed no significant scores on NEO. Patients with treatment-resistant depression and low openness on NEO showed positive relationships with reward dependence and cooperativeness on the TCI.<h4>Conclusions</h4>Many studies have reported that depressed patients show high neuroticism, low extraversion and low conscientiousness on the NEO. Our study highlights low openness on the NEO, as a risk mediator in treatment-resistant depression. This newly identified trait should be included as a risk factor in treatment-resistant depression.
format article
author Michio Takahashi
Yukihiko Shirayama
Katsumasa Muneoka
Masatoshi Suzuki
Koichi Sato
Kenji Hashimoto
author_facet Michio Takahashi
Yukihiko Shirayama
Katsumasa Muneoka
Masatoshi Suzuki
Koichi Sato
Kenji Hashimoto
author_sort Michio Takahashi
title Low openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression.
title_short Low openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression.
title_full Low openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression.
title_fullStr Low openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression.
title_full_unstemmed Low openness on the revised NEO personality inventory as a risk factor for treatment-resistant depression.
title_sort low openness on the revised neo personality inventory as a risk factor for treatment-resistant depression.
publisher Public Library of Science (PLoS)
publishDate 2013
url https://doaj.org/article/e4332b6fc6544d82a5c367574b9e660c
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