The <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance

The <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance

ABSTRACT The filamentous fungus Aspergillus fumigatus can cause a distinct set of clinical disorders in humans. Invasive aspergillosis (IA) is the most common life-threatening fungal disease of immunocompromised humans. The mitogen-activated protein kinase (MAPK) signaling pathways are essential to...

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Autores principales: Eliciane Cevolani Mattos, Lilian Pereira Silva, Clara Valero, Patrícia Alves de Castro, Thaila Fernanda dos Reis, Liliane F. C. Ribeiro, Mark R. Marten, Rafael Silva-Rocha, Cauã Westmann, Carlos Henrique Tomich de Paula da Silva, Carlton Anthony Taft, Narjes Al-Furaiji, Michael Bromley, Uffe H. Mortensen, J. Philipp Benz, Neil Andrew Brown, Gustavo H. Goldman
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Aspergillus fumigatus
cell wall integrity pathway
MpkC
SakA
caspofungin
osmotic stress
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/e4362aac315c465db4926930d9ce17bc
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