Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis

The formation of new blood vessels requires both polarized cell migration and coordinated control of endothelial cell contacts. Here, Cao and colleagues describe at the sub-cellular level the cytoskeletal and cell junction dynamics regulating these processes upon VEGF-induced cell elongation.

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Autores principales:	Jiahui Cao, Manuel Ehling, Sigrid März, Jochen Seebach, Katsiaryna Tarbashevich, Tomas Sixta, Mara E. Pitulescu, Ann-Cathrin Werner, Boris Flach, Eloi Montanez, Erez Raz, Ralf H. Adams, Hans Schnittler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e445ed86f1b4415cb0e943b34a211150
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spelling	oai:doaj.org-article:e445ed86f1b4415cb0e943b34a2111502021-12-02T15:38:54ZPolarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis10.1038/s41467-017-02373-82041-1723https://doaj.org/article/e445ed86f1b4415cb0e943b34a2111502017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02373-8https://doaj.org/toc/2041-1723The formation of new blood vessels requires both polarized cell migration and coordinated control of endothelial cell contacts. Here, Cao and colleagues describe at the sub-cellular level the cytoskeletal and cell junction dynamics regulating these processes upon VEGF-induced cell elongation.Jiahui CaoManuel EhlingSigrid MärzJochen SeebachKatsiaryna TarbashevichTomas SixtaMara E. PitulescuAnn-Cathrin WernerBoris FlachEloi MontanezErez RazRalf H. AdamsHans SchnittlerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-20 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiahui Cao Manuel Ehling Sigrid März Jochen Seebach Katsiaryna Tarbashevich Tomas Sixta Mara E. Pitulescu Ann-Cathrin Werner Boris Flach Eloi Montanez Erez Raz Ralf H. Adams Hans Schnittler Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
description	The formation of new blood vessels requires both polarized cell migration and coordinated control of endothelial cell contacts. Here, Cao and colleagues describe at the sub-cellular level the cytoskeletal and cell junction dynamics regulating these processes upon VEGF-induced cell elongation.
format	article
author	Jiahui Cao Manuel Ehling Sigrid März Jochen Seebach Katsiaryna Tarbashevich Tomas Sixta Mara E. Pitulescu Ann-Cathrin Werner Boris Flach Eloi Montanez Erez Raz Ralf H. Adams Hans Schnittler
author_facet	Jiahui Cao Manuel Ehling Sigrid März Jochen Seebach Katsiaryna Tarbashevich Tomas Sixta Mara E. Pitulescu Ann-Cathrin Werner Boris Flach Eloi Montanez Erez Raz Ralf H. Adams Hans Schnittler
author_sort	Jiahui Cao
title	Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
title_short	Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
title_full	Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
title_fullStr	Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
title_full_unstemmed	Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
title_sort	polarized actin and ve-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e445ed86f1b4415cb0e943b34a211150
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Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis

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