Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites

Tools for imaging epigenetic modifications can shed light on the regulation of epigenetic processes. Here, the authors present a fluorescence complementation approach for detection of DNA and histone methylation at endogenous genomic sites allowing following of dynamic changes of these marks by live...

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Main Authors:	Cristiana Lungu, Sabine Pinter, Julian Broche, Philipp Rathert, Albert Jeltsch
Format:	article
Language:	EN
Published:	Nature Portfolio 2017
Subjects:	Science Q
Online Access:	https://doaj.org/article/e44e3b2e78014a09bf15e0148a8b7e32
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id	oai:doaj.org-article:e44e3b2e78014a09bf15e0148a8b7e32
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spelling	oai:doaj.org-article:e44e3b2e78014a09bf15e0148a8b7e322021-12-02T15:38:57ZModular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites10.1038/s41467-017-00457-z2041-1723https://doaj.org/article/e44e3b2e78014a09bf15e0148a8b7e322017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00457-zhttps://doaj.org/toc/2041-1723Tools for imaging epigenetic modifications can shed light on the regulation of epigenetic processes. Here, the authors present a fluorescence complementation approach for detection of DNA and histone methylation at endogenous genomic sites allowing following of dynamic changes of these marks by live-cell microscopy.Cristiana LunguSabine PinterJulian BrochePhilipp RathertAlbert JeltschNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cristiana Lungu Sabine Pinter Julian Broche Philipp Rathert Albert Jeltsch Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites
description	Tools for imaging epigenetic modifications can shed light on the regulation of epigenetic processes. Here, the authors present a fluorescence complementation approach for detection of DNA and histone methylation at endogenous genomic sites allowing following of dynamic changes of these marks by live-cell microscopy.
format	article
author	Cristiana Lungu Sabine Pinter Julian Broche Philipp Rathert Albert Jeltsch
author_facet	Cristiana Lungu Sabine Pinter Julian Broche Philipp Rathert Albert Jeltsch
author_sort	Cristiana Lungu
title	Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites
title_short	Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites
title_full	Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites
title_fullStr	Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites
title_full_unstemmed	Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites
title_sort	modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e44e3b2e78014a09bf15e0148a8b7e32
work_keys_str_mv	AT cristianalungu modularfluorescencecomplementationsensorsforlivecelldetectionofepigeneticsignalsatendogenousgenomicsites AT sabinepinter modularfluorescencecomplementationsensorsforlivecelldetectionofepigeneticsignalsatendogenousgenomicsites AT julianbroche modularfluorescencecomplementationsensorsforlivecelldetectionofepigeneticsignalsatendogenousgenomicsites AT philipprathert modularfluorescencecomplementationsensorsforlivecelldetectionofepigeneticsignalsatendogenousgenomicsites AT albertjeltsch modularfluorescencecomplementationsensorsforlivecelldetectionofepigeneticsignalsatendogenousgenomicsites
_version_	1718386023685160960

Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites

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