Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit
Drosophila larvae are able to perform visually-guided behaviours yet the molecular and circuit mechanisms for discriminating changes in light intensity are not known. Here, the authors report that ON versus OFF discrimination results from opposing cholinergic and glutamatergic mechanisms.
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Nature Portfolio
2019
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oai:doaj.org-article:e467524c74324b62a2891cf668aa2be62021-12-02T14:38:36ZMuscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit10.1038/s41467-019-12104-w2041-1723https://doaj.org/article/e467524c74324b62a2891cf668aa2be62019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12104-whttps://doaj.org/toc/2041-1723Drosophila larvae are able to perform visually-guided behaviours yet the molecular and circuit mechanisms for discriminating changes in light intensity are not known. Here, the authors report that ON versus OFF discrimination results from opposing cholinergic and glutamatergic mechanisms.Bo QinTim-Henning HumbergAnna KimHyong S. KimJacob ShortFengqiu DiaoBenjamin H. WhiteSimon G. SprecherQuan YuanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
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Science Q Bo Qin Tim-Henning Humberg Anna Kim Hyong S. Kim Jacob Short Fengqiu Diao Benjamin H. White Simon G. Sprecher Quan Yuan Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit |
description |
Drosophila larvae are able to perform visually-guided behaviours yet the molecular and circuit mechanisms for discriminating changes in light intensity are not known. Here, the authors report that ON versus OFF discrimination results from opposing cholinergic and glutamatergic mechanisms. |
format |
article |
author |
Bo Qin Tim-Henning Humberg Anna Kim Hyong S. Kim Jacob Short Fengqiu Diao Benjamin H. White Simon G. Sprecher Quan Yuan |
author_facet |
Bo Qin Tim-Henning Humberg Anna Kim Hyong S. Kim Jacob Short Fengqiu Diao Benjamin H. White Simon G. Sprecher Quan Yuan |
author_sort |
Bo Qin |
title |
Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit |
title_short |
Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit |
title_full |
Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit |
title_fullStr |
Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit |
title_full_unstemmed |
Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit |
title_sort |
muscarinic acetylcholine receptor signaling generates off selectivity in a simple visual circuit |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/e467524c74324b62a2891cf668aa2be6 |
work_keys_str_mv |
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