Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit

Drosophila larvae are able to perform visually-guided behaviours yet the molecular and circuit mechanisms for discriminating changes in light intensity are not known. Here, the authors report that ON versus OFF discrimination results from opposing cholinergic and glutamatergic mechanisms.

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Autores principales: Bo Qin, Tim-Henning Humberg, Anna Kim, Hyong S. Kim, Jacob Short, Fengqiu Diao, Benjamin H. White, Simon G. Sprecher, Quan Yuan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e467524c74324b62a2891cf668aa2be6
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spelling oai:doaj.org-article:e467524c74324b62a2891cf668aa2be62021-12-02T14:38:36ZMuscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit10.1038/s41467-019-12104-w2041-1723https://doaj.org/article/e467524c74324b62a2891cf668aa2be62019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12104-whttps://doaj.org/toc/2041-1723Drosophila larvae are able to perform visually-guided behaviours yet the molecular and circuit mechanisms for discriminating changes in light intensity are not known. Here, the authors report that ON versus OFF discrimination results from opposing cholinergic and glutamatergic mechanisms.Bo QinTim-Henning HumbergAnna KimHyong S. KimJacob ShortFengqiu DiaoBenjamin H. WhiteSimon G. SprecherQuan YuanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bo Qin
Tim-Henning Humberg
Anna Kim
Hyong S. Kim
Jacob Short
Fengqiu Diao
Benjamin H. White
Simon G. Sprecher
Quan Yuan
Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit
description Drosophila larvae are able to perform visually-guided behaviours yet the molecular and circuit mechanisms for discriminating changes in light intensity are not known. Here, the authors report that ON versus OFF discrimination results from opposing cholinergic and glutamatergic mechanisms.
format article
author Bo Qin
Tim-Henning Humberg
Anna Kim
Hyong S. Kim
Jacob Short
Fengqiu Diao
Benjamin H. White
Simon G. Sprecher
Quan Yuan
author_facet Bo Qin
Tim-Henning Humberg
Anna Kim
Hyong S. Kim
Jacob Short
Fengqiu Diao
Benjamin H. White
Simon G. Sprecher
Quan Yuan
author_sort Bo Qin
title Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit
title_short Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit
title_full Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit
title_fullStr Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit
title_full_unstemmed Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit
title_sort muscarinic acetylcholine receptor signaling generates off selectivity in a simple visual circuit
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e467524c74324b62a2891cf668aa2be6
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