Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

How the cardiac myocyte epigenome is rearranged during development, postnatal maturation and disease is not well understood. Here, the authors investigate the human cardiac myocyte epigenome during development and chronic heart failure and identify distinct epigenetic programs regulating these proce...

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Autores principales:	Ralf Gilsbach, Martin Schwaderer, Sebastian Preissl, Björn A. Grüning, David Kranzhöfer, Pedro Schneider, Thomas G. Nührenberg, Sonia Mulero-Navarro, Dieter Weichenhan, Christian Braun, Martina Dreßen, Adam R. Jacobs, Harald Lahm, Torsten Doenst, Rolf Backofen, Markus Krane, Bruce D. Gelb, Lutz Hein
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e46b79bc29434dea9a7d59690c85ee94
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spelling	oai:doaj.org-article:e46b79bc29434dea9a7d59690c85ee942021-12-02T16:56:57ZDistinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo10.1038/s41467-017-02762-z2041-1723https://doaj.org/article/e46b79bc29434dea9a7d59690c85ee942018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02762-zhttps://doaj.org/toc/2041-1723How the cardiac myocyte epigenome is rearranged during development, postnatal maturation and disease is not well understood. Here, the authors investigate the human cardiac myocyte epigenome during development and chronic heart failure and identify distinct epigenetic programs regulating these processes.Ralf GilsbachMartin SchwadererSebastian PreisslBjörn A. GrüningDavid KranzhöferPedro SchneiderThomas G. NührenbergSonia Mulero-NavarroDieter WeichenhanChristian BraunMartina DreßenAdam R. JacobsHarald LahmTorsten DoenstRolf BackofenMarkus KraneBruce D. GelbLutz HeinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ralf Gilsbach Martin Schwaderer Sebastian Preissl Björn A. Grüning David Kranzhöfer Pedro Schneider Thomas G. Nührenberg Sonia Mulero-Navarro Dieter Weichenhan Christian Braun Martina Dreßen Adam R. Jacobs Harald Lahm Torsten Doenst Rolf Backofen Markus Krane Bruce D. Gelb Lutz Hein Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo
description	How the cardiac myocyte epigenome is rearranged during development, postnatal maturation and disease is not well understood. Here, the authors investigate the human cardiac myocyte epigenome during development and chronic heart failure and identify distinct epigenetic programs regulating these processes.
format	article
author	Ralf Gilsbach Martin Schwaderer Sebastian Preissl Björn A. Grüning David Kranzhöfer Pedro Schneider Thomas G. Nührenberg Sonia Mulero-Navarro Dieter Weichenhan Christian Braun Martina Dreßen Adam R. Jacobs Harald Lahm Torsten Doenst Rolf Backofen Markus Krane Bruce D. Gelb Lutz Hein
author_facet	Ralf Gilsbach Martin Schwaderer Sebastian Preissl Björn A. Grüning David Kranzhöfer Pedro Schneider Thomas G. Nührenberg Sonia Mulero-Navarro Dieter Weichenhan Christian Braun Martina Dreßen Adam R. Jacobs Harald Lahm Torsten Doenst Rolf Backofen Markus Krane Bruce D. Gelb Lutz Hein
author_sort	Ralf Gilsbach
title	Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo
title_short	Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo
title_full	Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo
title_fullStr	Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo
title_full_unstemmed	Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo
title_sort	distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e46b79bc29434dea9a7d59690c85ee94
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Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

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