Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment

Liza S Köster,1 Remo G Lobetti,2 Patrick Kelly1 1Department of Clinical Sciences, One Health Center for Zoonoses and Tropical Veterinary Medicine, Ross University School of Veterinary Medicine, St Kitts, West Indies; 2Bryanston Veterinary Hospital, Bryanston, South Africa Abstract: Canine...

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Autores principales:	Köster LS, Lobetti RG, Kelly P
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/e46bf9656d7e4608b55d8aec20a7cf27
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spelling	oai:doaj.org-article:e46bf9656d7e4608b55d8aec20a7cf272021-12-02T02:06:47ZCanine babesiosis: a perspective on clinical complications, biomarkers, and treatment2230-2034https://doaj.org/article/e46bf9656d7e4608b55d8aec20a7cf272015-04-01T00:00:00Zhttp://www.dovepress.com/canine-babesiosis-a-perspective-on-clinical-complications-biomarkers-a-peer-reviewed-article-VMRRhttps://doaj.org/toc/2230-2034 Liza S Köster,1 Remo G Lobetti,2 Patrick Kelly1 1Department of Clinical Sciences, One Health Center for Zoonoses and Tropical Veterinary Medicine, Ross University School of Veterinary Medicine, St Kitts, West Indies; 2Bryanston Veterinary Hospital, Bryanston, South Africa Abstract: Canine babesiosis is a common tick transmitted disease of dogs worldwide. A number of Babesia sp. can infect dogs and the spectrum is increasing as molecular methods are developed to differentiate organisms. Clinical signs are generally attributed to hemolysis caused by the organisms in the erythrocytes but in some animals with some Babesia spp. there can be an immune mediated component to the anemia and/or a severe inflammatory reaction associated. This complicated form of canine babesiosis is associated with high morbidity and mortality. A variety of clinical markers has been investigated to enable clinicians to provide more accurate prognoses and adapt their treatments which vary according to the infecting species. In this review, we discuss the taxonomy, clinical signs, diagnostic imaging, clinical biomarkers, treatment, and prophylaxis of one of the most common and important diseases of dogs worldwide. Keywords: babesiosis, vector-borne disease, dogKöster LSLobetti RGKelly PDove Medical PressarticleVeterinary medicineSF600-1100ENVeterinary Medicine: Research and Reports, Vol 2015, Iss default, Pp 119-128 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Veterinary medicine SF600-1100
spellingShingle	Veterinary medicine SF600-1100 Köster LS Lobetti RG Kelly P Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment
description	Liza S Köster,1 Remo G Lobetti,2 Patrick Kelly1 1Department of Clinical Sciences, One Health Center for Zoonoses and Tropical Veterinary Medicine, Ross University School of Veterinary Medicine, St Kitts, West Indies; 2Bryanston Veterinary Hospital, Bryanston, South Africa Abstract: Canine babesiosis is a common tick transmitted disease of dogs worldwide. A number of Babesia sp. can infect dogs and the spectrum is increasing as molecular methods are developed to differentiate organisms. Clinical signs are generally attributed to hemolysis caused by the organisms in the erythrocytes but in some animals with some Babesia spp. there can be an immune mediated component to the anemia and/or a severe inflammatory reaction associated. This complicated form of canine babesiosis is associated with high morbidity and mortality. A variety of clinical markers has been investigated to enable clinicians to provide more accurate prognoses and adapt their treatments which vary according to the infecting species. In this review, we discuss the taxonomy, clinical signs, diagnostic imaging, clinical biomarkers, treatment, and prophylaxis of one of the most common and important diseases of dogs worldwide. Keywords: babesiosis, vector-borne disease, dog
format	article
author	Köster LS Lobetti RG Kelly P
author_facet	Köster LS Lobetti RG Kelly P
author_sort	Köster LS
title	Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment
title_short	Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment
title_full	Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment
title_fullStr	Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment
title_full_unstemmed	Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment
title_sort	canine babesiosis: a perspective on clinical complications, biomarkers, and treatment
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/e46bf9656d7e4608b55d8aec20a7cf27
work_keys_str_mv	AT kosterls caninebabesiosisaperspectiveonclinicalcomplicationsbiomarkersandtreatment AT lobettirg caninebabesiosisaperspectiveonclinicalcomplicationsbiomarkersandtreatment AT kellyp caninebabesiosisaperspectiveonclinicalcomplicationsbiomarkersandtreatment
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Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment

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