Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism
Abstract Iron status is known to be associated with the physiology of adipose tissue (AT). We aimed to investigate AT heme and expression of heme exporter (FLVCR1) in association with obesity and type 2 diabetes (T2D). Substantial amounts of FLVCR1 mRNA and protein levels were detected in AT, being...
Guardado en:
Autores principales: | José María Moreno-Navarrete, Amaia Rodríguez, Francisco Ortega, Sara Becerril, Mònica Sabater-Masdeu, Jessica Latorre, Wifredo Ricart, Gema Frühbeck, José Manuel Fernández-Real |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e46d89855e2748d69d10d87f6683d7c9 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Deletion of inducible nitric-oxide synthase in leptin-deficient mice improves brown adipose tissue function.
por: Sara Becerril, et al.
Publicado: (2010) -
Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.
por: Amandine Girousse, et al.
Publicado: (2013) -
Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis
por: Karla J. Suchacki, et al.
Publicado: (2020) -
Normalization of adiponectin concentrations by leptin replacement in ob/ob mice is accompanied by reductions in systemic oxidative stress and inflammation
por: Gema Frühbeck, et al.
Publicado: (2017) -
Brown adipose tissue is the key depot for glucose clearance in microbiota depleted mice
por: Min Li, et al.
Publicado: (2021)