Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions

The transportation of large molecules through the vascular endothelium presents a major challenge forin vivodrug delivery. Here, the authors demonstrate the potential of using external magnetic fields and magnetic nanoparticles to enhance the local extravasation of circulating large molecules.

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Auteurs principaux:	Yongzhi Qiu, Sheng Tong, Linlin Zhang, Yumiko Sakurai, David R. Myers, Lin Hong, Wilbur A. Lam, Gang Bao
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/e46df2218ab044b5b981f4c1ffa07ffd
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id	oai:doaj.org-article:e46df2218ab044b5b981f4c1ffa07ffd
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spelling	oai:doaj.org-article:e46df2218ab044b5b981f4c1ffa07ffd2021-12-02T17:06:05ZMagnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions10.1038/ncomms155942041-1723https://doaj.org/article/e46df2218ab044b5b981f4c1ffa07ffd2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15594https://doaj.org/toc/2041-1723The transportation of large molecules through the vascular endothelium presents a major challenge forin vivodrug delivery. Here, the authors demonstrate the potential of using external magnetic fields and magnetic nanoparticles to enhance the local extravasation of circulating large molecules.Yongzhi QiuSheng TongLinlin ZhangYumiko SakuraiDavid R. MyersLin HongWilbur A. LamGang BaoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yongzhi Qiu Sheng Tong Linlin Zhang Yumiko Sakurai David R. Myers Lin Hong Wilbur A. Lam Gang Bao Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions
description	The transportation of large molecules through the vascular endothelium presents a major challenge forin vivodrug delivery. Here, the authors demonstrate the potential of using external magnetic fields and magnetic nanoparticles to enhance the local extravasation of circulating large molecules.
format	article
author	Yongzhi Qiu Sheng Tong Linlin Zhang Yumiko Sakurai David R. Myers Lin Hong Wilbur A. Lam Gang Bao
author_facet	Yongzhi Qiu Sheng Tong Linlin Zhang Yumiko Sakurai David R. Myers Lin Hong Wilbur A. Lam Gang Bao
author_sort	Yongzhi Qiu
title	Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions
title_short	Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions
title_full	Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions
title_fullStr	Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions
title_full_unstemmed	Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions
title_sort	magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e46df2218ab044b5b981f4c1ffa07ffd
work_keys_str_mv	AT yongzhiqiu magneticforcesenablecontrolleddrugdeliverybydisruptingendothelialcellcelljunctions AT shengtong magneticforcesenablecontrolleddrugdeliverybydisruptingendothelialcellcelljunctions AT linlinzhang magneticforcesenablecontrolleddrugdeliverybydisruptingendothelialcellcelljunctions AT yumikosakurai magneticforcesenablecontrolleddrugdeliverybydisruptingendothelialcellcelljunctions AT davidrmyers magneticforcesenablecontrolleddrugdeliverybydisruptingendothelialcellcelljunctions AT linhong magneticforcesenablecontrolleddrugdeliverybydisruptingendothelialcellcelljunctions AT wilburalam magneticforcesenablecontrolleddrugdeliverybydisruptingendothelialcellcelljunctions AT gangbao magneticforcesenablecontrolleddrugdeliverybydisruptingendothelialcellcelljunctions
_version_	1718381763425730560

Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions

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