Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes

Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes

Abstract Hepatitis C virus (HCV) infection of hepatocytes promotes liver fibrosis by activation of hepatic stellate cells (HSCs) and excessive deposition of extracellular matrix in liver tissue. Whether or not host factors released from the HCV-infected hepatocytes play role in HSCs activation is un...

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Bibliographic Details
Main Authors: Ju-Chien Cheng, Ching-Ping Tseng, Mei-Huei Liao, Cheng-Yuan Peng, Jau-Song Yu, Po-Heng Chuang, Jing-Tang Huang, Jeremy J. W. Chen
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e46f0db66ae743b08ca8c05f3e859002
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