Substrate and cell fusion influence on slime mold network dynamics

Abstract The acellular slime mold Physarum polycephalum provides an excellent model to study network formation, as its network is remodelled constantly in response to mass gain/loss and environmental conditions. How slime molds networks are built and fuse to allow for efficient exploration and adapt...

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Autores principales:	Fernando Patino-Ramirez, Chloé Arson, Audrey Dussutour
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e472334cb0b0448b92c23bb7a9bd6870
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spelling	oai:doaj.org-article:e472334cb0b0448b92c23bb7a9bd68702021-12-02T14:12:42ZSubstrate and cell fusion influence on slime mold network dynamics10.1038/s41598-020-80320-22045-2322https://doaj.org/article/e472334cb0b0448b92c23bb7a9bd68702021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80320-2https://doaj.org/toc/2045-2322Abstract The acellular slime mold Physarum polycephalum provides an excellent model to study network formation, as its network is remodelled constantly in response to mass gain/loss and environmental conditions. How slime molds networks are built and fuse to allow for efficient exploration and adaptation to environmental conditions is still not fully understood. Here, we characterize the network organization of slime molds exploring homogeneous neutral, nutritive and adverse environments. We developed a fully automated image analysis method to extract the network topology and followed the slime molds before and after fusion. Our results show that: (1) slime molds build sparse networks with thin veins in a neutral environment and more compact networks with thicker veins in a nutritive or adverse environment; (2) slime molds construct long, efficient and resilient networks in neutral and adverse environments, whereas in nutritive environments, they build shorter and more centralized networks; and (3) slime molds fuse rapidly and establish multiple connections with their clone-mates in a neutral environment, whereas they display a late fusion with fewer connections in an adverse environment. Our study demonstrates that slime mold networks evolve continuously via pruning and reinforcement, adapting to different environmental conditions.Fernando Patino-RamirezChloé ArsonAudrey DussutourNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Fernando Patino-Ramirez Chloé Arson Audrey Dussutour Substrate and cell fusion influence on slime mold network dynamics
description	Abstract The acellular slime mold Physarum polycephalum provides an excellent model to study network formation, as its network is remodelled constantly in response to mass gain/loss and environmental conditions. How slime molds networks are built and fuse to allow for efficient exploration and adaptation to environmental conditions is still not fully understood. Here, we characterize the network organization of slime molds exploring homogeneous neutral, nutritive and adverse environments. We developed a fully automated image analysis method to extract the network topology and followed the slime molds before and after fusion. Our results show that: (1) slime molds build sparse networks with thin veins in a neutral environment and more compact networks with thicker veins in a nutritive or adverse environment; (2) slime molds construct long, efficient and resilient networks in neutral and adverse environments, whereas in nutritive environments, they build shorter and more centralized networks; and (3) slime molds fuse rapidly and establish multiple connections with their clone-mates in a neutral environment, whereas they display a late fusion with fewer connections in an adverse environment. Our study demonstrates that slime mold networks evolve continuously via pruning and reinforcement, adapting to different environmental conditions.
format	article
author	Fernando Patino-Ramirez Chloé Arson Audrey Dussutour
author_facet	Fernando Patino-Ramirez Chloé Arson Audrey Dussutour
author_sort	Fernando Patino-Ramirez
title	Substrate and cell fusion influence on slime mold network dynamics
title_short	Substrate and cell fusion influence on slime mold network dynamics
title_full	Substrate and cell fusion influence on slime mold network dynamics
title_fullStr	Substrate and cell fusion influence on slime mold network dynamics
title_full_unstemmed	Substrate and cell fusion influence on slime mold network dynamics
title_sort	substrate and cell fusion influence on slime mold network dynamics
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e472334cb0b0448b92c23bb7a9bd6870
work_keys_str_mv	AT fernandopatinoramirez substrateandcellfusioninfluenceonslimemoldnetworkdynamics AT chloearson substrateandcellfusioninfluenceonslimemoldnetworkdynamics AT audreydussutour substrateandcellfusioninfluenceonslimemoldnetworkdynamics
_version_	1718391817409396736

Substrate and cell fusion influence on slime mold network dynamics

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