DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy

5-hydroxymethylation of cysteine (5-hmC) plays a role in epigenetic regulation. Here the authors analyse the hydroxymethylome in embryonic, neonatal, adult and hypertrophic mouse cardiomyocytes and show that the dynamic modulation of hydroxymethylated DNA is important for cardiomyocyte gene expressi...

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Autores principales:	Carolina M. Greco, Paolo Kunderfranco, Marcello Rubino, Veronica Larcher, Pierluigi Carullo, Achille Anselmo, Kerstin Kurz, Thomas Carell, Andrea Angius, Michael V. G. Latronico, Roberto Papait, Gianluigi Condorelli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e4744c07ca8d4762ae057ee6d346f450
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spelling	oai:doaj.org-article:e4744c07ca8d4762ae057ee6d346f4502021-12-02T16:58:00ZDNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy10.1038/ncomms124182041-1723https://doaj.org/article/e4744c07ca8d4762ae057ee6d346f4502016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12418https://doaj.org/toc/2041-17235-hydroxymethylation of cysteine (5-hmC) plays a role in epigenetic regulation. Here the authors analyse the hydroxymethylome in embryonic, neonatal, adult and hypertrophic mouse cardiomyocytes and show that the dynamic modulation of hydroxymethylated DNA is important for cardiomyocyte gene expression programming in heart development and failure.Carolina M. GrecoPaolo KunderfrancoMarcello RubinoVeronica LarcherPierluigi CarulloAchille AnselmoKerstin KurzThomas CarellAndrea AngiusMichael V. G. LatronicoRoberto PapaitGianluigi CondorelliNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Carolina M. Greco Paolo Kunderfranco Marcello Rubino Veronica Larcher Pierluigi Carullo Achille Anselmo Kerstin Kurz Thomas Carell Andrea Angius Michael V. G. Latronico Roberto Papait Gianluigi Condorelli DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy
description	5-hydroxymethylation of cysteine (5-hmC) plays a role in epigenetic regulation. Here the authors analyse the hydroxymethylome in embryonic, neonatal, adult and hypertrophic mouse cardiomyocytes and show that the dynamic modulation of hydroxymethylated DNA is important for cardiomyocyte gene expression programming in heart development and failure.
format	article
author	Carolina M. Greco Paolo Kunderfranco Marcello Rubino Veronica Larcher Pierluigi Carullo Achille Anselmo Kerstin Kurz Thomas Carell Andrea Angius Michael V. G. Latronico Roberto Papait Gianluigi Condorelli
author_facet	Carolina M. Greco Paolo Kunderfranco Marcello Rubino Veronica Larcher Pierluigi Carullo Achille Anselmo Kerstin Kurz Thomas Carell Andrea Angius Michael V. G. Latronico Roberto Papait Gianluigi Condorelli
author_sort	Carolina M. Greco
title	DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy
title_short	DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy
title_full	DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy
title_fullStr	DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy
title_full_unstemmed	DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy
title_sort	dna hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/e4744c07ca8d4762ae057ee6d346f450
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DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy

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