UMI-linked consensus sequencing enables phylogenetic analysis of directed evolution
The success of protein evolution is dependent on the sequence context mutations are introduced into. Here the authors present UMIC-seq that allows consensus generation for closely related genes by using unique molecular identifiers linked to gene variants.
Guardado en:
Autores principales: | Paul Jannis Zurek, Philipp Knyphausen, Katharina Neufeld, Ahir Pushpanath, Florian Hollfelder |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e4783caa57744ab09ff2474ed8ee0e3c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
- Oceanography of Japan / Umi no Kenkyu
-
Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis
por: Stephane Emond, et al.
Publicado: (2020) -
Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA
por: Thomas L. Dunwell, et al.
Publicado: (2021) -
What Is an “Arachnid”? Consensus, Consilience, and Confirmation Bias in the Phylogenetics of Chelicerata
por: Prashant P. Sharma, et al.
Publicado: (2021) -
Entropy Evolution in Consensus Networks
por: Shuangshuang Fu, et al.
Publicado: (2017)