Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay

To date the carboacylation of alkenes has been reported only in single- and two-component methodologies. Here, the authors report a three-component nickel-catalyzed carboacylation of olefins which enables the rapid construction of ketones with high levels of complexity and diversity.

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Detalles Bibliográficos
Autores principales: Xian Zhao, Hai-Yong Tu, Lei Guo, Shengqing Zhu, Feng-Ling Qing, Lingling Chu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/e47c110e45244dd8aba2aefe8589ec40
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Sumario:To date the carboacylation of alkenes has been reported only in single- and two-component methodologies. Here, the authors report a three-component nickel-catalyzed carboacylation of olefins which enables the rapid construction of ketones with high levels of complexity and diversity.