Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the People's Republic of China

Meiwen Yu,1,* Kan Wu,1,* Bing Pei,2 Degang Yang,2 Qiulin Wang,1 Hongsheng Wang,1 Jianping Shen,1 Liangbing Yan,1 Guochen Zhang1 1Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People&am...

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Autores principales: Yu MW, Wu K, Pei B, Yang DG, Wang QL, Wang HS, Shen JP, Yan LB, Zhang GC
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Lenguaje:EN
Publicado: Dove Medical Press 2013
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Acceso en línea:https://doaj.org/article/e487d715621147d0976ce6eef1283bed
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spelling oai:doaj.org-article:e487d715621147d0976ce6eef1283bed2021-12-02T00:33:31ZRifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the People's Republic of China1178-1998https://doaj.org/article/e487d715621147d0976ce6eef1283bed2013-08-01T00:00:00Zhttps://www.dovepress.com/rifampicin-resistant-mycobacterium-leprae-in-an-elderly-leprosy-patien-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Meiwen Yu,1,* Kan Wu,1,* Bing Pei,2 Degang Yang,2 Qiulin Wang,1 Hongsheng Wang,1 Jianping Shen,1 Liangbing Yan,1 Guochen Zhang1 1Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People's Republic of China; 2Department of Infectious Diseases, Shanghai Skin Disease Hospital, Shanghai, People's Republic of China *These authors contributed equally to this work Abstract: The reported number of registered leprosy patients worldwide declined with the introduction of multidrug therapy. However, the emergence of rifampicin resistance in leprosy patients engenders difficulties for an individual patient, and its dissemination could pose a threat to leprosy control. This study reports an elderly patient who was diagnosed with rifampicin-resistant lepromatous leprosy. This case indicates that inadequate treatment and poor compliance may eventually result in rifampicin resistance in Mycobacterium leprae and clinical relapse. Keywords: leprosy, rifampicin, drug resistance, elderly patientYu MWWu KPei BYang DGWang QLWang HSShen JPYan LBZhang GCDove Medical Pressarticleleprosyrifampcindrug resistanceolder patientGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 8, Pp 1097-1099 (2013)
institution DOAJ
collection DOAJ
language EN
topic leprosy
rifampcin
drug resistance
older patient
Geriatrics
RC952-954.6
spellingShingle leprosy
rifampcin
drug resistance
older patient
Geriatrics
RC952-954.6
Yu MW
Wu K
Pei B
Yang DG
Wang QL
Wang HS
Shen JP
Yan LB
Zhang GC
Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the People's Republic of China
description Meiwen Yu,1,* Kan Wu,1,* Bing Pei,2 Degang Yang,2 Qiulin Wang,1 Hongsheng Wang,1 Jianping Shen,1 Liangbing Yan,1 Guochen Zhang1 1Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for STD and Leprosy Control, China CDC, Nanjing, People's Republic of China; 2Department of Infectious Diseases, Shanghai Skin Disease Hospital, Shanghai, People's Republic of China *These authors contributed equally to this work Abstract: The reported number of registered leprosy patients worldwide declined with the introduction of multidrug therapy. However, the emergence of rifampicin resistance in leprosy patients engenders difficulties for an individual patient, and its dissemination could pose a threat to leprosy control. This study reports an elderly patient who was diagnosed with rifampicin-resistant lepromatous leprosy. This case indicates that inadequate treatment and poor compliance may eventually result in rifampicin resistance in Mycobacterium leprae and clinical relapse. Keywords: leprosy, rifampicin, drug resistance, elderly patient
format article
author Yu MW
Wu K
Pei B
Yang DG
Wang QL
Wang HS
Shen JP
Yan LB
Zhang GC
author_facet Yu MW
Wu K
Pei B
Yang DG
Wang QL
Wang HS
Shen JP
Yan LB
Zhang GC
author_sort Yu MW
title Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the People's Republic of China
title_short Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the People's Republic of China
title_full Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the People's Republic of China
title_fullStr Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the People's Republic of China
title_full_unstemmed Rifampicin-resistant Mycobacterium leprae in an elderly leprosy patient in the People's Republic of China
title_sort rifampicin-resistant mycobacterium leprae in an elderly leprosy patient in the people's republic of china
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/e487d715621147d0976ce6eef1283bed
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