A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ

Many natural-product like drugs have a tetracyclic terpenoid core. Here, the authors developed a synthesis of triterpene-like tetracyclic systems, and apply this method to the preparation of a number of enantiomeric compounds, two of which are very selective ligands for estrogen receptor beta

Guardado en:
Detalles Bibliográficos
Autores principales: Wan Shin Kim, Zachary A. Shalit, Sidney M. Nguyen, Emmalie Schoepke, Alan Eastman, Thomas P. Burris, Arti B. Gaur, Glenn C. Micalizio
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/e48d05268db34d77806be736c82cc8ae
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares