COMPARISION OF PRE-OPERATIVE ON DANSETRON VERSUS COMBINATION OF DEXAMETHASONE AND ONDANSETRON FOR POSTOPERATIVE NAUSEA

Objective: To compare the efficacy of ondansetron with a combination of ondansetron and dexamethasone after elective laparoscopic cholecystectomy in terms of postoperative nausea and vomiting. Study Design: Randomized controlled trial. Place and Duration of Study: Department of Surgery, Com...

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Autores principales:	Mansoor Tariq Azim, Syed Mukarram Hussain, Muhammad Mudasir Saleem, Eisha Manzoor, Mishal Pervaiz
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	dexamethasone elective laparoscopic cholecystectomy postoperative nausea and vomiting Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/e48f91907f874a35b1a240ea26f142c2
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spelling	oai:doaj.org-article:e48f91907f874a35b1a240ea26f142c22021-11-29T03:00:34ZCOMPARISION OF PRE-OPERATIVE ON DANSETRON VERSUS COMBINATION OF DEXAMETHASONE AND ONDANSETRON FOR POSTOPERATIVE NAUSEA0030-96482411-8842https://doaj.org/article/e48f91907f874a35b1a240ea26f142c22018-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2589/2115https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the efficacy of ondansetron with a combination of ondansetron and dexamethasone after elective laparoscopic cholecystectomy in terms of postoperative nausea and vomiting. Study Design: Randomized controlled trial. Place and Duration of Study: Department of Surgery, Combined Military Hospital Rawalpindi Pakistan, from Apr 2014 to Mar 2015. Materials and Methods: Two hundred and twenty two patients fulfilling the inclusion criteria were selected for study and divided into two groups of 111 each. Group A was given ondansetron while group B was given combination of ondansetron and dexamethasone at induction of general anesthesia. Patients of both groups were observed at 24 hours postoperatively for nausea and vomiting. Results: Sixty six patients in group A had nausea as compared to 50 patients in group B (p-value 0.03), 46 patients in group A had vomiting as compared to 19 patients in group B (p-value <0.001), showing statistically significant difference between the two groups. Conclusion: Postoperative nausea and vomiting is significantly lower in ondansetron and dexamethasone combination group as compared to ondansetron alone group after elective laparoscopic cholecystectomy.Mansoor Tariq AzimSyed Mukarram HussainMuhammad Mudasir SaleemEisha ManzoorMishal PervaizArmy Medical College Rawalpindiarticledexamethasoneelective laparoscopic cholecystectomypostoperative nausea and vomitingMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 6, Pp 1711-1715 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	dexamethasone elective laparoscopic cholecystectomy postoperative nausea and vomiting Medicine R Medicine (General) R5-920
spellingShingle	dexamethasone elective laparoscopic cholecystectomy postoperative nausea and vomiting Medicine R Medicine (General) R5-920 Mansoor Tariq Azim Syed Mukarram Hussain Muhammad Mudasir Saleem Eisha Manzoor Mishal Pervaiz COMPARISION OF PRE-OPERATIVE ON DANSETRON VERSUS COMBINATION OF DEXAMETHASONE AND ONDANSETRON FOR POSTOPERATIVE NAUSEA
description	Objective: To compare the efficacy of ondansetron with a combination of ondansetron and dexamethasone after elective laparoscopic cholecystectomy in terms of postoperative nausea and vomiting. Study Design: Randomized controlled trial. Place and Duration of Study: Department of Surgery, Combined Military Hospital Rawalpindi Pakistan, from Apr 2014 to Mar 2015. Materials and Methods: Two hundred and twenty two patients fulfilling the inclusion criteria were selected for study and divided into two groups of 111 each. Group A was given ondansetron while group B was given combination of ondansetron and dexamethasone at induction of general anesthesia. Patients of both groups were observed at 24 hours postoperatively for nausea and vomiting. Results: Sixty six patients in group A had nausea as compared to 50 patients in group B (p-value 0.03), 46 patients in group A had vomiting as compared to 19 patients in group B (p-value <0.001), showing statistically significant difference between the two groups. Conclusion: Postoperative nausea and vomiting is significantly lower in ondansetron and dexamethasone combination group as compared to ondansetron alone group after elective laparoscopic cholecystectomy.
format	article
author	Mansoor Tariq Azim Syed Mukarram Hussain Muhammad Mudasir Saleem Eisha Manzoor Mishal Pervaiz
author_facet	Mansoor Tariq Azim Syed Mukarram Hussain Muhammad Mudasir Saleem Eisha Manzoor Mishal Pervaiz
author_sort	Mansoor Tariq Azim
title	COMPARISION OF PRE-OPERATIVE ON DANSETRON VERSUS COMBINATION OF DEXAMETHASONE AND ONDANSETRON FOR POSTOPERATIVE NAUSEA
title_short	COMPARISION OF PRE-OPERATIVE ON DANSETRON VERSUS COMBINATION OF DEXAMETHASONE AND ONDANSETRON FOR POSTOPERATIVE NAUSEA
title_full	COMPARISION OF PRE-OPERATIVE ON DANSETRON VERSUS COMBINATION OF DEXAMETHASONE AND ONDANSETRON FOR POSTOPERATIVE NAUSEA
title_fullStr	COMPARISION OF PRE-OPERATIVE ON DANSETRON VERSUS COMBINATION OF DEXAMETHASONE AND ONDANSETRON FOR POSTOPERATIVE NAUSEA
title_full_unstemmed	COMPARISION OF PRE-OPERATIVE ON DANSETRON VERSUS COMBINATION OF DEXAMETHASONE AND ONDANSETRON FOR POSTOPERATIVE NAUSEA
title_sort	comparision of pre-operative on dansetron versus combination of dexamethasone and ondansetron for postoperative nausea
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/e48f91907f874a35b1a240ea26f142c2
work_keys_str_mv	AT mansoortariqazim comparisionofpreoperativeondansetronversuscombinationofdexamethasoneandondansetronforpostoperativenausea AT syedmukarramhussain comparisionofpreoperativeondansetronversuscombinationofdexamethasoneandondansetronforpostoperativenausea AT muhammadmudasirsaleem comparisionofpreoperativeondansetronversuscombinationofdexamethasoneandondansetronforpostoperativenausea AT eishamanzoor comparisionofpreoperativeondansetronversuscombinationofdexamethasoneandondansetronforpostoperativenausea AT mishalpervaiz comparisionofpreoperativeondansetronversuscombinationofdexamethasoneandondansetronforpostoperativenausea
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COMPARISION OF PRE-OPERATIVE ON DANSETRON VERSUS COMBINATION OF DEXAMETHASONE AND ONDANSETRON FOR POSTOPERATIVE NAUSEA

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