IL-1β mediated nanoscale surface clustering of integrin α5β1 regulates the adhesion of mesenchymal stem cells

IL-1β mediated nanoscale surface clustering of integrin α5β1 regulates the adhesion of mesenchymal stem cells

Abstract Clinical use of human mesenchymal stem cells (hMSCs) is limited due to their rapid clearance, reducing their therapeutic efficacy. The inflammatory cytokine IL-1β activates hMSCs and is known to enhance their engraftment. Consequently, understanding the molecular mechanism of this inflammat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Stephanie A. Maynard, Ekaterina Pchelintseva, Limor Zwi-Dantsis, Anika Nagelkerke, Sahana Gopal, Yuri E. Korchev, Andrew Shevchuk, Molly M. Stevens
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e49047eb91214a098278bf3e0eedaf80
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares