New View on Dietary Fiber Selection for Predictable Shifts in Gut Microbiota

ABSTRACT Dietary fibers can be utilized to shape the human gut microbiota. However, the outcomes from most dietary fibers currently used as prebiotics are a result of competition between microbes with overlapping abilities to utilize these fibers. Thus, divergent fiber responses are observed across...

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Autores principales:	T. M. Cantu-Jungles, B. R. Hamaker
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2020
Materias:	dietary fiber gut microbiota fiber specificity fiber response Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/e4944271191247aeaf507fc28bb314cb
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spelling	oai:doaj.org-article:e4944271191247aeaf507fc28bb314cb2021-11-15T15:56:58ZNew View on Dietary Fiber Selection for Predictable Shifts in Gut Microbiota10.1128/mBio.02179-192150-7511https://doaj.org/article/e4944271191247aeaf507fc28bb314cb2020-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02179-19https://doaj.org/toc/2150-7511ABSTRACT Dietary fibers can be utilized to shape the human gut microbiota. However, the outcomes from most dietary fibers currently used as prebiotics are a result of competition between microbes with overlapping abilities to utilize these fibers. Thus, divergent fiber responses are observed across individuals harboring distinct microbial communities. Here, we propose that dietary fibers can be classified hierarchically according to their specificity toward gut microbes. Highly specific fibers harbor chemical and physical characteristics that allow them to be utilized by only a narrow group of bacteria within the gut, reducing competition for that substrate. The use of such fibers as prebiotics targeted to specific microbes would result in predictable shifts independent of the background microbial composition.T. M. Cantu-JunglesB. R. HamakerAmerican Society for Microbiologyarticledietary fibergut microbiotafiber specificityfiber responseMicrobiologyQR1-502ENmBio, Vol 11, Iss 1 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	dietary fiber gut microbiota fiber specificity fiber response Microbiology QR1-502
spellingShingle	dietary fiber gut microbiota fiber specificity fiber response Microbiology QR1-502 T. M. Cantu-Jungles B. R. Hamaker New View on Dietary Fiber Selection for Predictable Shifts in Gut Microbiota
description	ABSTRACT Dietary fibers can be utilized to shape the human gut microbiota. However, the outcomes from most dietary fibers currently used as prebiotics are a result of competition between microbes with overlapping abilities to utilize these fibers. Thus, divergent fiber responses are observed across individuals harboring distinct microbial communities. Here, we propose that dietary fibers can be classified hierarchically according to their specificity toward gut microbes. Highly specific fibers harbor chemical and physical characteristics that allow them to be utilized by only a narrow group of bacteria within the gut, reducing competition for that substrate. The use of such fibers as prebiotics targeted to specific microbes would result in predictable shifts independent of the background microbial composition.
format	article
author	T. M. Cantu-Jungles B. R. Hamaker
author_facet	T. M. Cantu-Jungles B. R. Hamaker
author_sort	T. M. Cantu-Jungles
title	New View on Dietary Fiber Selection for Predictable Shifts in Gut Microbiota
title_short	New View on Dietary Fiber Selection for Predictable Shifts in Gut Microbiota
title_full	New View on Dietary Fiber Selection for Predictable Shifts in Gut Microbiota
title_fullStr	New View on Dietary Fiber Selection for Predictable Shifts in Gut Microbiota
title_full_unstemmed	New View on Dietary Fiber Selection for Predictable Shifts in Gut Microbiota
title_sort	new view on dietary fiber selection for predictable shifts in gut microbiota
publisher	American Society for Microbiology
publishDate	2020
url	https://doaj.org/article/e4944271191247aeaf507fc28bb314cb
work_keys_str_mv	AT tmcantujungles newviewondietaryfiberselectionforpredictableshiftsingutmicrobiota AT brhamaker newviewondietaryfiberselectionforpredictableshiftsingutmicrobiota
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New View on Dietary Fiber Selection for Predictable Shifts in Gut Microbiota

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