High glucose induced c-Met activation promotes aggressive phenotype and regulates expression of glucose metabolism genes in HCC cells

High glucose induced c-Met activation promotes aggressive phenotype and regulates expression of glucose metabolism genes in HCC cells

Abstract Hepatocellular carcinoma (HCC) is strongly associated with metabolic dysregulations/deregulations and hyperglycemia is a common metabolic disturbance in metabolic diseases. Hyperglycemia is defined to promote epithelial to mesenchymal transition (EMT) of cancer cells in various cancers but...

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Autores principales: Hande Topel, Ezgi Bağırsakçı, Yeliz Yılmaz, Ayşim Güneş, Gülsün Bağcı, Dehan Çömez, Erkan Kahraman, Peyda Korhan, Neşe Atabey
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e495cb6e91344c98bfe6a3d0b13b04ca
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