Influence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population

Abstract Whether elevated beat-to-beat blood pressure variability (BPV) has an influence on vascular elasticity is confounded and poorly understood. This study hypothesized that the increased BPV could have an adverse effect on the vascular elasticity, as estimated by total arterial compliance (TAC)...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yufa Xia, Xin Liu, Dan Wu, Huahua Xiong, Lijie Ren, Lin Xu, Wanqing Wu, Heye Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e49bf348608a446184a2a7fa85e4beca
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e49bf348608a446184a2a7fa85e4beca
record_format	dspace
spelling	oai:doaj.org-article:e49bf348608a446184a2a7fa85e4beca2021-12-02T12:31:55ZInfluence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population10.1038/s41598-017-08640-42045-2322https://doaj.org/article/e49bf348608a446184a2a7fa85e4beca2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08640-4https://doaj.org/toc/2045-2322Abstract Whether elevated beat-to-beat blood pressure variability (BPV) has an influence on vascular elasticity is confounded and poorly understood. This study hypothesized that the increased BPV could have an adverse effect on the vascular elasticity, as estimated by total arterial compliance (TAC), independent of blood pressure (BP) values. Beat-to-beat BP and TAC were measured in 81 hypertensive patients (experimental population) and in 80 normal adults (control population). Beat-to-beat BPV was assessed by standard deviation (SD), average real variability (ARV), residual standard deviation (RSD) and variation independent of mean (VIM). In experimental population, systolic BPV (SBPV) showed a significant correlation with TAC (SD, r = −0.326, p < 0.001; ARV, r = −0.277, p = 0.003; RSD, r = −0.382, p < 0.001; VIM, r = −0.274, p = 0.003); similarly, SD, RSD and VIM of diastolic BP (DBP) also showed explicit correlation with TAC (r = −0.255, p = 0.006; r = −0.289, p = 0.002; r = −0.219, p = 0.019; respectively). However, in the control population, neither SBPV nor diastolic BPV (DBPV) showed a significant correlation with TAC. Furthermore, in the experimental population, VIM of systolic BP (SBP) was also a determinant of TAC (β = −0.100, p = 0.040) independent of average SBP, DBP, age and body mass index. In conclusion, these data imply that beat-to-beat BPV, especially SBPV, shows an independent correlation with vascular elasticity in hypertensive population.Yufa XiaXin LiuDan WuHuahua XiongLijie RenLin XuWanqing WuHeye ZhangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yufa Xia Xin Liu Dan Wu Huahua Xiong Lijie Ren Lin Xu Wanqing Wu Heye Zhang Influence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population
description	Abstract Whether elevated beat-to-beat blood pressure variability (BPV) has an influence on vascular elasticity is confounded and poorly understood. This study hypothesized that the increased BPV could have an adverse effect on the vascular elasticity, as estimated by total arterial compliance (TAC), independent of blood pressure (BP) values. Beat-to-beat BP and TAC were measured in 81 hypertensive patients (experimental population) and in 80 normal adults (control population). Beat-to-beat BPV was assessed by standard deviation (SD), average real variability (ARV), residual standard deviation (RSD) and variation independent of mean (VIM). In experimental population, systolic BPV (SBPV) showed a significant correlation with TAC (SD, r = −0.326, p < 0.001; ARV, r = −0.277, p = 0.003; RSD, r = −0.382, p < 0.001; VIM, r = −0.274, p = 0.003); similarly, SD, RSD and VIM of diastolic BP (DBP) also showed explicit correlation with TAC (r = −0.255, p = 0.006; r = −0.289, p = 0.002; r = −0.219, p = 0.019; respectively). However, in the control population, neither SBPV nor diastolic BPV (DBPV) showed a significant correlation with TAC. Furthermore, in the experimental population, VIM of systolic BP (SBP) was also a determinant of TAC (β = −0.100, p = 0.040) independent of average SBP, DBP, age and body mass index. In conclusion, these data imply that beat-to-beat BPV, especially SBPV, shows an independent correlation with vascular elasticity in hypertensive population.
format	article
author	Yufa Xia Xin Liu Dan Wu Huahua Xiong Lijie Ren Lin Xu Wanqing Wu Heye Zhang
author_facet	Yufa Xia Xin Liu Dan Wu Huahua Xiong Lijie Ren Lin Xu Wanqing Wu Heye Zhang
author_sort	Yufa Xia
title	Influence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population
title_short	Influence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population
title_full	Influence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population
title_fullStr	Influence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population
title_full_unstemmed	Influence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population
title_sort	influence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e49bf348608a446184a2a7fa85e4beca
work_keys_str_mv	AT yufaxia influenceofbeattobeatbloodpressurevariabilityonvascularelasticityinhypertensivepopulation AT xinliu influenceofbeattobeatbloodpressurevariabilityonvascularelasticityinhypertensivepopulation AT danwu influenceofbeattobeatbloodpressurevariabilityonvascularelasticityinhypertensivepopulation AT huahuaxiong influenceofbeattobeatbloodpressurevariabilityonvascularelasticityinhypertensivepopulation AT lijieren influenceofbeattobeatbloodpressurevariabilityonvascularelasticityinhypertensivepopulation AT linxu influenceofbeattobeatbloodpressurevariabilityonvascularelasticityinhypertensivepopulation AT wanqingwu influenceofbeattobeatbloodpressurevariabilityonvascularelasticityinhypertensivepopulation AT heyezhang influenceofbeattobeatbloodpressurevariabilityonvascularelasticityinhypertensivepopulation
_version_	1718394249989324800

Influence of beat-to-beat blood pressure variability on vascular elasticity in hypertensive population

Ejemplares similares