PRODUCTION OF RECOMBINANT PROTEIN CRM197 IN ESCHERICHIA COLI
The CRM197 is a non-toxic mutant of diphtheria toxin having a single amino acid substitution of a glycine for a glutamic acid in position 52. Being naturally nontoxic, CRM197 is a promising adjuvant and ideal carrier protein for conjugate vaccines. Typically, production of diphtheria toxin and some...
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Autores principales: | I. V. Dukhovlinov, E. A. Fedorova, E. G. Bogomolova, O. A. Dobrovolskaya, E. N. Chernyaeva, R. I. Al-Shekhadat, A. S. Simbirtsev |
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Formato: | article |
Lenguaje: | RU |
Publicado: |
Sankt-Peterburg : NIIÈM imeni Pastera
2015
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Materias: | |
Acceso en línea: | https://doaj.org/article/e4a638dcdd2c4d69b05b095dff972fac |
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