Risperidone in the treatment of behavioral disorders associated with autism in children and adolescents

Roberto Canitano, Valeria ScandurraDivision of Child Neuropsychiatry, University Hospital of Siena, Siena, ItalyAbstract: This is a review of the clinical trials investigating the efficacy and safety of risperidone in the treatment of children with autistic spectrum disorders (ASD). The main clinica...

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Autores principales: Roberto Canitano, Valeria Scandurra
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Lenguaje:EN
Publicado: Dove Medical Press 2008
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Acceso en línea:https://doaj.org/article/e4a6b97264674637b7e1c69527753fa8
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spelling oai:doaj.org-article:e4a6b97264674637b7e1c69527753fa82021-12-02T02:17:49ZRisperidone in the treatment of behavioral disorders associated with autism in children and adolescents1176-63281178-2021https://doaj.org/article/e4a6b97264674637b7e1c69527753fa82008-09-01T00:00:00Zhttp://www.dovepress.com/risperidone-in-the-treatment-of-behavioral-disorders-associated-with-a-a2197https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Roberto Canitano, Valeria ScandurraDivision of Child Neuropsychiatry, University Hospital of Siena, Siena, ItalyAbstract: This is a review of the clinical trials investigating the efficacy and safety of risperidone in the treatment of children with autistic spectrum disorders (ASD). The main clinical characteristics are impairment in social skills, communication difficulties, repetitive movements and behaviors, including stereotypies. Pharmacotherapy is mainly directed at the so-called target symptoms, ie, behavioral disorders and the various kinds of repetitions associated with ASD. According to the available data, risperidone seems to be moderately efficacious and safe for treating behavioral disorders. 4 double blind controlled trial. 3 reanalysis studies, and 12 open studies have documented the role of risperidone in children with ASD. Controlled studies have been thoroughly considered in this review.Keywords: autism, pervasive developmental disorders, risperidone Roberto CanitanoValeria ScandurraDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 4, Pp 723-730 (2008)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Roberto Canitano
Valeria Scandurra
Risperidone in the treatment of behavioral disorders associated with autism in children and adolescents
description Roberto Canitano, Valeria ScandurraDivision of Child Neuropsychiatry, University Hospital of Siena, Siena, ItalyAbstract: This is a review of the clinical trials investigating the efficacy and safety of risperidone in the treatment of children with autistic spectrum disorders (ASD). The main clinical characteristics are impairment in social skills, communication difficulties, repetitive movements and behaviors, including stereotypies. Pharmacotherapy is mainly directed at the so-called target symptoms, ie, behavioral disorders and the various kinds of repetitions associated with ASD. According to the available data, risperidone seems to be moderately efficacious and safe for treating behavioral disorders. 4 double blind controlled trial. 3 reanalysis studies, and 12 open studies have documented the role of risperidone in children with ASD. Controlled studies have been thoroughly considered in this review.Keywords: autism, pervasive developmental disorders, risperidone
format article
author Roberto Canitano
Valeria Scandurra
author_facet Roberto Canitano
Valeria Scandurra
author_sort Roberto Canitano
title Risperidone in the treatment of behavioral disorders associated with autism in children and adolescents
title_short Risperidone in the treatment of behavioral disorders associated with autism in children and adolescents
title_full Risperidone in the treatment of behavioral disorders associated with autism in children and adolescents
title_fullStr Risperidone in the treatment of behavioral disorders associated with autism in children and adolescents
title_full_unstemmed Risperidone in the treatment of behavioral disorders associated with autism in children and adolescents
title_sort risperidone in the treatment of behavioral disorders associated with autism in children and adolescents
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/e4a6b97264674637b7e1c69527753fa8
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