Circulating Tumor Cells as a Novel Prostate Cancer Diagnostic Tool

The current screening test for prostate cancer (PCa) has the weak point of a high false-negative rate and a low true positive rate. There is an extreme need for a new and accurate testing system. Circulating Tumor Cells (CTCs) as the main liquid biopsy components provide excellent biomarkers for ear...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Fatemeh Khatami, Mandana Hasanzad
Format: article
Langue:EN
Publié: Urology Research Center 2020
Sujets:
Accès en ligne:https://doaj.org/article/e4a7a1e2bb81432fba647a281a2133e2
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
Description
Résumé:The current screening test for prostate cancer (PCa) has the weak point of a high false-negative rate and a low true positive rate. There is an extreme need for a new and accurate testing system. Circulating Tumor Cells (CTCs) as the main liquid biopsy components provide excellent biomarkers for early diagnosis of PCa, prognosis, recurrence risk, and treatment efficacy. These tumor cells can get the release of tumor and freely circulate in the patient’s body fluids and easily are traceable to answer the presence of the tumor more than its stage. The new gifted ISET®-CTC Test is a simple blood test with high sensitivity and specificity for the detection of CTC in PCa. As a novel idea, it is a challengeable point nowadays that it needs further studies.