Titrating bacterial growth and chemical biosynthesis for efficient N-acetylglucosamine and N-acetylneuraminic acid bioproduction

An imbalance between cell growth and bioproduction of engineered microbes often reduces production efficiency. Here, the authors report genetic code expansion-based cell growth and biosynthesis balance engineering to achieve high levels production of N-acetylglucosamine in E. coli and N-acetylneuram...

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Autores principales: Rongzhen Tian, Yanfeng Liu, Yanting Cao, Zhongjie Zhang, Jianghua Li, Long Liu, Guocheng Du, Jian Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/e4b1b57ed51e46f89bf4ce6ab7559907
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