Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death

It is unclear whether 2D metal dichalcogenides (TMD) alone can cause ferroptotic cell death. Here, the authors show TMD nanosheets induced ferroptosis in mammalian cell lines and in a mouse model after aspiration of TMD materials into lungs, causing ferroptotic cell death.

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Detalles Bibliográficos
Autores principales: Shujuan Xu, Huizhen Zheng, Ronglin Ma, Di Wu, Yanxia Pan, Chunyang Yin, Meng Gao, Weili Wang, Wei Li, Sijin Liu, Zhifang Chai, Ruibin Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/e4b1da3323cd4276b0d143ad62458143
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Sumario:It is unclear whether 2D metal dichalcogenides (TMD) alone can cause ferroptotic cell death. Here, the authors show TMD nanosheets induced ferroptosis in mammalian cell lines and in a mouse model after aspiration of TMD materials into lungs, causing ferroptotic cell death.