Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
It is unclear whether 2D metal dichalcogenides (TMD) alone can cause ferroptotic cell death. Here, the authors show TMD nanosheets induced ferroptosis in mammalian cell lines and in a mouse model after aspiration of TMD materials into lungs, causing ferroptotic cell death.
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Nature Portfolio
2020
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oai:doaj.org-article:e4b1da3323cd4276b0d143ad624581432021-12-02T18:36:59ZVacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death10.1038/s41467-020-17300-72041-1723https://doaj.org/article/e4b1da3323cd4276b0d143ad624581432020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17300-7https://doaj.org/toc/2041-1723It is unclear whether 2D metal dichalcogenides (TMD) alone can cause ferroptotic cell death. Here, the authors show TMD nanosheets induced ferroptosis in mammalian cell lines and in a mouse model after aspiration of TMD materials into lungs, causing ferroptotic cell death.Shujuan XuHuizhen ZhengRonglin MaDi WuYanxia PanChunyang YinMeng GaoWeili WangWei LiSijin LiuZhifang ChaiRuibin LiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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Science Q Shujuan Xu Huizhen Zheng Ronglin Ma Di Wu Yanxia Pan Chunyang Yin Meng Gao Weili Wang Wei Li Sijin Liu Zhifang Chai Ruibin Li Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death |
description |
It is unclear whether 2D metal dichalcogenides (TMD) alone can cause ferroptotic cell death. Here, the authors show TMD nanosheets induced ferroptosis in mammalian cell lines and in a mouse model after aspiration of TMD materials into lungs, causing ferroptotic cell death. |
format |
article |
author |
Shujuan Xu Huizhen Zheng Ronglin Ma Di Wu Yanxia Pan Chunyang Yin Meng Gao Weili Wang Wei Li Sijin Liu Zhifang Chai Ruibin Li |
author_facet |
Shujuan Xu Huizhen Zheng Ronglin Ma Di Wu Yanxia Pan Chunyang Yin Meng Gao Weili Wang Wei Li Sijin Liu Zhifang Chai Ruibin Li |
author_sort |
Shujuan Xu |
title |
Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death |
title_short |
Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death |
title_full |
Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death |
title_fullStr |
Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death |
title_full_unstemmed |
Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death |
title_sort |
vacancies on 2d transition metal dichalcogenides elicit ferroptotic cell death |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/e4b1da3323cd4276b0d143ad62458143 |
work_keys_str_mv |
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1718377892389322752 |