Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death

It is unclear whether 2D metal dichalcogenides (TMD) alone can cause ferroptotic cell death. Here, the authors show TMD nanosheets induced ferroptosis in mammalian cell lines and in a mouse model after aspiration of TMD materials into lungs, causing ferroptotic cell death.

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Autores principales: Shujuan Xu, Huizhen Zheng, Ronglin Ma, Di Wu, Yanxia Pan, Chunyang Yin, Meng Gao, Weili Wang, Wei Li, Sijin Liu, Zhifang Chai, Ruibin Li
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/e4b1da3323cd4276b0d143ad62458143
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spelling oai:doaj.org-article:e4b1da3323cd4276b0d143ad624581432021-12-02T18:36:59ZVacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death10.1038/s41467-020-17300-72041-1723https://doaj.org/article/e4b1da3323cd4276b0d143ad624581432020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17300-7https://doaj.org/toc/2041-1723It is unclear whether 2D metal dichalcogenides (TMD) alone can cause ferroptotic cell death. Here, the authors show TMD nanosheets induced ferroptosis in mammalian cell lines and in a mouse model after aspiration of TMD materials into lungs, causing ferroptotic cell death.Shujuan XuHuizhen ZhengRonglin MaDi WuYanxia PanChunyang YinMeng GaoWeili WangWei LiSijin LiuZhifang ChaiRuibin LiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shujuan Xu
Huizhen Zheng
Ronglin Ma
Di Wu
Yanxia Pan
Chunyang Yin
Meng Gao
Weili Wang
Wei Li
Sijin Liu
Zhifang Chai
Ruibin Li
Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
description It is unclear whether 2D metal dichalcogenides (TMD) alone can cause ferroptotic cell death. Here, the authors show TMD nanosheets induced ferroptosis in mammalian cell lines and in a mouse model after aspiration of TMD materials into lungs, causing ferroptotic cell death.
format article
author Shujuan Xu
Huizhen Zheng
Ronglin Ma
Di Wu
Yanxia Pan
Chunyang Yin
Meng Gao
Weili Wang
Wei Li
Sijin Liu
Zhifang Chai
Ruibin Li
author_facet Shujuan Xu
Huizhen Zheng
Ronglin Ma
Di Wu
Yanxia Pan
Chunyang Yin
Meng Gao
Weili Wang
Wei Li
Sijin Liu
Zhifang Chai
Ruibin Li
author_sort Shujuan Xu
title Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
title_short Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
title_full Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
title_fullStr Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
title_full_unstemmed Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
title_sort vacancies on 2d transition metal dichalcogenides elicit ferroptotic cell death
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/e4b1da3323cd4276b0d143ad62458143
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