Restless arms syndrome: prevalence, impact, and management strategies

Elisabeth Ruppert1–31Sleep Disorders Center - CIRCSom, Department of Neurology, Hôpital Civil, 67091 Strasbourg, France; 2Faculty of Medicine, University of Strasbourg, 67000 Strasbourg, France; 3Institute for Cellular and Integrative Neurosciences, CNRS - UPR 3212, University of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autor principal:	Ruppert E
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	RLS variant RLS equivalent restless upper limb restless of upper extremities Willis-Ekbom disease periodic arm movements Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/e4b3825840974104bebe14f4c3f24930
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e4b3825840974104bebe14f4c3f24930
record_format	dspace
spelling	oai:doaj.org-article:e4b3825840974104bebe14f4c3f249302021-12-02T04:53:02ZRestless arms syndrome: prevalence, impact, and management strategies1178-2021https://doaj.org/article/e4b3825840974104bebe14f4c3f249302019-07-01T00:00:00Zhttps://www.dovepress.com/restless-arms-syndrome-prevalence-impact-and-management-strategies-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Elisabeth Ruppert1–31Sleep Disorders Center - CIRCSom, Department of Neurology, Hôpital Civil, 67091 Strasbourg, France; 2Faculty of Medicine, University of Strasbourg, 67000 Strasbourg, France; 3Institute for Cellular and Integrative Neurosciences, CNRS - UPR 3212, University of Strasbourg, 67000 Strasbourg, FranceAbstract: This literature review focuses on restless arms syndrome (RAS), an upper limb variant of restless legs syndrome (RLS). RLS, also known as Willis-Ekbom disease, is a frequently occurring neurological disorder characterized by an irresistible urge to move the lower limbs often accompanied by unpleasant sensations in the legs, worsened at rest and in the evening, improved by movement. Extension of leg restlessness to the upper limbs is frequently reported in typical patients who had RLS only in the legs and usually occurs later in the course of RLS, restlessness remaining most invalidating in the lower limbs. In RAS, the arms are predominantly affected with little or no involvement of the legs. Cases of restless shoulders syndrome or periodic arm movements without arm restlessness were not considered. A total of 9 articles with 10 cases were included and analyzed for the adherence to the five essential diagnostic criteria of the International RLS Study Group (IRLSSG) classification, as well as for the additional supportive features. All of the reported cases were classified as having definite RAS. The clinical history and disease evolution of two previously reported patients were completed and updated. Overall, the clinical picture of RAS does not differ from that of RLS, except for the symptoms localization on the upper limbs. Underlying mechanisms of the spread of RLS to upper limb restlessness and of RAS remain unknown. Whether RAS is a phenotypic variant of RLS or a separate entity needs further investigations. RAS likely remains underdiagnosed and according to IRLSSG diagnostic criteria RAS should be considered when RLS-like symptoms are present in one or both arms, especially when they have a circadian pattern and are improved by movement and dopaminergic therapy. Clinicians should be aware of this rare condition, especially as treatment using dopaminergic agonists proves to be very efficient.Keywords: RLS variant, RLS equivalent, restless upper limb, restlessness of upper extremities, Willis-Ekbom disease, periodic arm movementsRuppert EDove Medical PressarticleRLS variantRLS equivalentrestless upper limbrestless of upper extremitiesWillis-Ekbom diseaseperiodic arm movementsNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 15, Pp 1737-1750 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	RLS variant RLS equivalent restless upper limb restless of upper extremities Willis-Ekbom disease periodic arm movements Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	RLS variant RLS equivalent restless upper limb restless of upper extremities Willis-Ekbom disease periodic arm movements Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Ruppert E Restless arms syndrome: prevalence, impact, and management strategies
description	Elisabeth Ruppert1–31Sleep Disorders Center - CIRCSom, Department of Neurology, Hôpital Civil, 67091 Strasbourg, France; 2Faculty of Medicine, University of Strasbourg, 67000 Strasbourg, France; 3Institute for Cellular and Integrative Neurosciences, CNRS - UPR 3212, University of Strasbourg, 67000 Strasbourg, FranceAbstract: This literature review focuses on restless arms syndrome (RAS), an upper limb variant of restless legs syndrome (RLS). RLS, also known as Willis-Ekbom disease, is a frequently occurring neurological disorder characterized by an irresistible urge to move the lower limbs often accompanied by unpleasant sensations in the legs, worsened at rest and in the evening, improved by movement. Extension of leg restlessness to the upper limbs is frequently reported in typical patients who had RLS only in the legs and usually occurs later in the course of RLS, restlessness remaining most invalidating in the lower limbs. In RAS, the arms are predominantly affected with little or no involvement of the legs. Cases of restless shoulders syndrome or periodic arm movements without arm restlessness were not considered. A total of 9 articles with 10 cases were included and analyzed for the adherence to the five essential diagnostic criteria of the International RLS Study Group (IRLSSG) classification, as well as for the additional supportive features. All of the reported cases were classified as having definite RAS. The clinical history and disease evolution of two previously reported patients were completed and updated. Overall, the clinical picture of RAS does not differ from that of RLS, except for the symptoms localization on the upper limbs. Underlying mechanisms of the spread of RLS to upper limb restlessness and of RAS remain unknown. Whether RAS is a phenotypic variant of RLS or a separate entity needs further investigations. RAS likely remains underdiagnosed and according to IRLSSG diagnostic criteria RAS should be considered when RLS-like symptoms are present in one or both arms, especially when they have a circadian pattern and are improved by movement and dopaminergic therapy. Clinicians should be aware of this rare condition, especially as treatment using dopaminergic agonists proves to be very efficient.Keywords: RLS variant, RLS equivalent, restless upper limb, restlessness of upper extremities, Willis-Ekbom disease, periodic arm movements
format	article
author	Ruppert E
author_facet	Ruppert E
author_sort	Ruppert E
title	Restless arms syndrome: prevalence, impact, and management strategies
title_short	Restless arms syndrome: prevalence, impact, and management strategies
title_full	Restless arms syndrome: prevalence, impact, and management strategies
title_fullStr	Restless arms syndrome: prevalence, impact, and management strategies
title_full_unstemmed	Restless arms syndrome: prevalence, impact, and management strategies
title_sort	restless arms syndrome: prevalence, impact, and management strategies
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/e4b3825840974104bebe14f4c3f24930
work_keys_str_mv	AT rupperte restlessarmssyndromeprevalenceimpactandmanagementstrategies
_version_	1718401041688428544

Restless arms syndrome: prevalence, impact, and management strategies

Ejemplares similares