Cardiac muscle thin filament structures reveal calcium regulatory mechanism

The contraction of cardiac and skeletal muscles is regulated by Ca2+ released from the sarcoplasmic reticulum in muscle cells. Here the authors provide molecular insights into Ca2+ regulation of muscle contraction by determining the cryo-EM structures of the human cardiac muscle thin filament in the...

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Autores principales:	Yurika Yamada, Keiichi Namba, Takashi Fujii
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e4bf2fe3a75243b9ab70287b5d826eb2
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id	oai:doaj.org-article:e4bf2fe3a75243b9ab70287b5d826eb2
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spelling	oai:doaj.org-article:e4bf2fe3a75243b9ab70287b5d826eb22021-12-02T14:40:27ZCardiac muscle thin filament structures reveal calcium regulatory mechanism10.1038/s41467-019-14008-12041-1723https://doaj.org/article/e4bf2fe3a75243b9ab70287b5d826eb22020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14008-1https://doaj.org/toc/2041-1723The contraction of cardiac and skeletal muscles is regulated by Ca2+ released from the sarcoplasmic reticulum in muscle cells. Here the authors provide molecular insights into Ca2+ regulation of muscle contraction by determining the cryo-EM structures of the human cardiac muscle thin filament in the absence and presence of Ca2+.Yurika YamadaKeiichi NambaTakashi FujiiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yurika Yamada Keiichi Namba Takashi Fujii Cardiac muscle thin filament structures reveal calcium regulatory mechanism
description	The contraction of cardiac and skeletal muscles is regulated by Ca2+ released from the sarcoplasmic reticulum in muscle cells. Here the authors provide molecular insights into Ca2+ regulation of muscle contraction by determining the cryo-EM structures of the human cardiac muscle thin filament in the absence and presence of Ca2+.
format	article
author	Yurika Yamada Keiichi Namba Takashi Fujii
author_facet	Yurika Yamada Keiichi Namba Takashi Fujii
author_sort	Yurika Yamada
title	Cardiac muscle thin filament structures reveal calcium regulatory mechanism
title_short	Cardiac muscle thin filament structures reveal calcium regulatory mechanism
title_full	Cardiac muscle thin filament structures reveal calcium regulatory mechanism
title_fullStr	Cardiac muscle thin filament structures reveal calcium regulatory mechanism
title_full_unstemmed	Cardiac muscle thin filament structures reveal calcium regulatory mechanism
title_sort	cardiac muscle thin filament structures reveal calcium regulatory mechanism
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e4bf2fe3a75243b9ab70287b5d826eb2
work_keys_str_mv	AT yurikayamada cardiacmusclethinfilamentstructuresrevealcalciumregulatorymechanism AT keiichinamba cardiacmusclethinfilamentstructuresrevealcalciumregulatorymechanism AT takashifujii cardiacmusclethinfilamentstructuresrevealcalciumregulatorymechanism
_version_	1718390329397215232

Cardiac muscle thin filament structures reveal calcium regulatory mechanism

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