Cardiac muscle thin filament structures reveal calcium regulatory mechanism
The contraction of cardiac and skeletal muscles is regulated by Ca2+ released from the sarcoplasmic reticulum in muscle cells. Here the authors provide molecular insights into Ca2+ regulation of muscle contraction by determining the cryo-EM structures of the human cardiac muscle thin filament in the...
Saved in:
Main Authors: | Yurika Yamada, Keiichi Namba, Takashi Fujii |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/e4bf2fe3a75243b9ab70287b5d826eb2 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Thick filament mechano-sensing is a calcium-independent regulatory mechanism in skeletal muscle
by: L. Fusi, et al.
Published: (2016) -
Structure of actomyosin rigour complex at 5.2 Å resolution and insights into the ATPase cycle mechanism
by: Takashi Fujii, et al.
Published: (2017) -
The molecular basis of thin filament activation: from single molecule to muscle
by: Thomas Longyear, et al.
Published: (2017) -
Redox regulation of calcium release in skeletal and cardiac muscle
by: HIDALGO,CECILIA, et al.
Published: (2002) -
Single-molecule imaging reveals the concerted release of myosin from regulated thin filaments
by: Quentin M Smith, et al.
Published: (2021)