Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet

The mechanism by which macromolecular catalysts use energy from exergonic reactions to move, adapt, and assemble has been unclear. In this Perspective article, R. Dean Astumian shows that in addition to disequilibrium of the catalyzed reaction, kinetic asymmetry is the essential feature required to...

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Autor principal:	R. Dean Astumian
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e4c02fcd69d14091b57450d7646e9e60
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spelling	oai:doaj.org-article:e4c02fcd69d14091b57450d7646e9e602021-12-02T15:35:30ZKinetic asymmetry allows macromolecular catalysts to drive an information ratchet10.1038/s41467-019-11402-72041-1723https://doaj.org/article/e4c02fcd69d14091b57450d7646e9e602019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11402-7https://doaj.org/toc/2041-1723The mechanism by which macromolecular catalysts use energy from exergonic reactions to move, adapt, and assemble has been unclear. In this Perspective article, R. Dean Astumian shows that in addition to disequilibrium of the catalyzed reaction, kinetic asymmetry is the essential feature required to drive non-equilibrium response by an information ratchet mechanism.R. Dean AstumianNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q R. Dean Astumian Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet
description	The mechanism by which macromolecular catalysts use energy from exergonic reactions to move, adapt, and assemble has been unclear. In this Perspective article, R. Dean Astumian shows that in addition to disequilibrium of the catalyzed reaction, kinetic asymmetry is the essential feature required to drive non-equilibrium response by an information ratchet mechanism.
format	article
author	R. Dean Astumian
author_facet	R. Dean Astumian
author_sort	R. Dean Astumian
title	Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet
title_short	Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet
title_full	Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet
title_fullStr	Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet
title_full_unstemmed	Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet
title_sort	kinetic asymmetry allows macromolecular catalysts to drive an information ratchet
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/e4c02fcd69d14091b57450d7646e9e60
work_keys_str_mv	AT rdeanastumian kineticasymmetryallowsmacromolecularcatalyststodriveaninformationratchet
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Kinetic asymmetry allows macromolecular catalysts to drive an information ratchet

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