Assembly of chromosome-scale contigs by efficiently resolving repetitive sequences with long reads
Repetitive sequences in complex eukaryote genomes can cause fragmented assemblies with incomplete gene sequences and unanchored or mispositioned contigs. Here, the authors report HERA, a method to improve genome assemblies by efficiently resolving repeats using single-molecule sequencing data.
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| Autores principales: | , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2019
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/e4cb5234c1a7488d86300fa3e1c6f161 |
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| Sumario: | Repetitive sequences in complex eukaryote genomes can cause fragmented assemblies with incomplete gene sequences and unanchored or mispositioned contigs. Here, the authors report HERA, a method to improve genome assemblies by efficiently resolving repeats using single-molecule sequencing data. |
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